2-hydroxythiophenol diacetic ester

Base Information

• Chemical Name: 2-hydroxythiophenol diacetic ester
• CAS No.: 73726-60-0
• Molecular Formula: C₁₀H₁₀O₃S
• Molecular Weight: 210.254
• Mol file: 73726-60-0.mol

Synonyms:2-hydroxythiophenol diacetic ester

Chemical Property of 2-hydroxythiophenol diacetic ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-hydroxythiophenol diacetic ester

There total 26 articles about 2-hydroxythiophenol diacetic ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-chloro-1,,3,2-benzoxathiastibole (61329-21-3) + acetyl chloride (75-36-5) → 2-hydroxythiophenol diacetic ester (73726-60-0)

Guidance literature:

In benzene; Heating;

Reference yield: 84.0%

spiro<1,3-benzoxathiole-2,1'-cyclohexane> (29026-66-2) + acetyl chloride (75-36-5) → 2-hydroxythiophenol diacetic ester (73726-60-0) + 5-acetylspiro<1,3-benzoxathiole-2,1'-cyclohexane> (91870-98-3)

Guidance literature:

With aluminium trichloride; In dichloromethane; at -10 ℃; for 1h;

Reference yield: 83.0%

spiro<1,3-benzoxathiole-2,1'-cyclopentane> (29026-65-1) + acetyl chloride (75-36-5) → 2-hydroxythiophenol diacetic ester (73726-60-0) + 5-acetylspiro<1,3-benzoxathiole-2,1'-cyclopentane> (91870-97-2)

Guidance literature:

With aluminium trichloride; In dichloromethane; at -10 ℃; for 1h;

upstream raw materials:

ortho-mercaptophenol

2-ethyl-2-methyl-benz[1,3]oxathiol

acetyl chloride

2,2-dimethylbenzo[d][1,3]oxathiole

Refernces

• 1、 Corda, Luciana,Fadda, Anna Maria,Maccioni, Antonio,Maccioni, Anna Maria,Podda, Gianni. "Studies on the Synthesis of Heterocyclic Compounds. XVI. Cleavage of 1,3-Benzodioxoles and -Benzoxathioles by Sodium Iodide-Acyl Chloride". . p. 311 - 314. Retrieved 2007/10/02.
• 2、 Bonsignore, Leonardo,Fadda, Anna Maria,Loy, Giuseppe,Maccioni, Anna Maria,Marongiu, Enrica,Podda, Gianni. "Studies on the Synthesis of Heterocyclic Compounds. XIV. Cleavage of 1,3-Benzoxathioles by Magnesium Bromide-Acetic Anhydride". . p. 573 - 576. Retrieved 2007/10/02.