Technology Process of C24H21N3O3
There total 3 articles about C24H21N3O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bis-triphenylphosphine-palladium(II) chloride; cesium fluoride;
In
water; N,N-dimethyl-formamide;
at 110 ℃;
for 0.166667h;
Microwave irradiation;
DOI:10.1016/j.bmcl.2012.01.116
- Guidance literature:
-
Multi-step reaction with 3 steps
1: copper(l) iodide; potassium phosphate; (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane / dimethyl sulfoxide / 22.5 h / 80 - 100 °C
2: bromine; sodium acetate / acetic acid / 72 h
3: bis-triphenylphosphine-palladium(II) chloride; cesium fluoride / water; N,N-dimethyl-formamide / 0.17 h / 110 °C / Microwave irradiation
With
bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; copper(l) iodide; (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane; bromine; sodium acetate; cesium fluoride;
In
water; acetic acid; dimethyl sulfoxide; N,N-dimethyl-formamide;
3: Suzuki coupling;
DOI:10.1016/j.bmcl.2012.01.116
- Guidance literature:
-
Multi-step reaction with 3 steps
1: copper(l) iodide; potassium phosphate; (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane / dimethyl sulfoxide / 22.5 h / 80 - 100 °C
2: bromine; sodium acetate / acetic acid / 72 h
3: bis-triphenylphosphine-palladium(II) chloride; cesium fluoride / water; N,N-dimethyl-formamide / 0.17 h / 110 °C / Microwave irradiation
With
bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; copper(l) iodide; (R,R)-N,N'-dimethyl-1,2-diaminocyclohexane; bromine; sodium acetate; cesium fluoride;
In
water; acetic acid; dimethyl sulfoxide; N,N-dimethyl-formamide;
3: Suzuki coupling;
DOI:10.1016/j.bmcl.2012.01.116