N-(1-(4-methoxyphenyl)ethyl)aniline

Base Information

• Chemical Name: N-(1-(4-methoxyphenyl)ethyl)aniline
• CAS No.: 128854-14-8
• Molecular Formula: C₁₅H₁₇NO
• Molecular Weight: 227.306
• Mol file: 128854-14-8.mol

Synonyms:N-(1-(4-methoxyphenyl)ethyl)aniline

Chemical Property of N-(1-(4-methoxyphenyl)ethyl)aniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(1-(4-methoxyphenyl)ethyl)aniline

There total 25 articles about N-(1-(4-methoxyphenyl)ethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(E)-N-(1-(4-methoxyphenyl)ethylidene)aniline (76154-08-0) → N-(1-(4-methoxyphenyl)ethyl)aniline (128854-14-8)

Guidance literature:

With trimethylamine-N-oxide; [bis(hexamethylene)cyclopentadienone]iron tricarbonyl; In isopropyl alcohol; at 100 ℃; for 18h; Inert atmosphere; Sealed tube;

DOI:10.1002/adsc.201701316

Reference yield: 98.0%

N-phenyl[1-(4-methoxyphenyl)ethylidene]amine (25287-28-9) → N-(1-(4-methoxyphenyl)ethyl)aniline (128854-14-8)

Guidance literature:

With 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; lithium bromide; In tetrahydrofuran; at 20 ℃; for 0.5h; chemoselective reaction;

DOI:10.1039/d0ra06023b

Reference yield: 96.0%

methyllithium (917-54-4) + p-methoxybenzylidene-phenylamine (836-41-9) → N-(1-(4-methoxyphenyl)ethyl)aniline (128854-14-8)

Guidance literature:

With choline chloride; In diethyl ether; glycerol; at 20 ℃; for 0.000833333h; chemoselective reaction;

DOI:10.1002/anie.201609929

upstream raw materials:

(E)-N-(1-(4-methoxyphenyl)ethylidene)aniline

1-(p-methoxyphenyl)ethyl bezenosulfonate

aniline

1-(p-methoxyphenyl)ethyl tosylate

Downstream raw materials:

N-phenyl[1-(4-methoxyphenyl)ethylidene]amine

Refernces

• 1、 Ma, Xiaodan,An, Zhe,Song, Hongyan,Shu, Xin,Xiang, Xu,He, Jing. "Atomic Pt-Catalyzed Heterogeneous Anti-Markovnikov C-N Formation: Pt10Activating N-H for Pt1δ+-Activated C-C Attack". . p. 9017 - 9027. Retrieved 2020.
• 2、 ?zdemir, ?smail,Dü?ünceli, Serpil Demir,Gürbüz, Nevin,Karaca, Emine ?zge. "Reduction hydrogenation of imines by in situ generated rhodium NHC complexes". . . Retrieved 2020.
• 3、 Beller, Matthias,Gawande, Manoj B.,Jagadeesh, Rajenahally V.,Kadam, Ravishankar G.,Li, Xinmin,Ma, Zhuang,Petr, Martin,Zbo?il, Radek,Zhou, Bei. "Reusable Co-nanoparticles for general and selectiveN-alkylation of amines and ammonia with alcohols". . p. 111 - 117. Retrieved 2022/01/06.
• 4、 Lin, Ying,Xie, Tian,Xu, Bing,Xu, Li,Ye, Xiang-Yang,Ye, Yang. "Benzyl thioether formation merging copper catalysis". . p. 692 - 697. Retrieved 2022/01/22.