Technology Process of tert-butyl ((2R,3S)-1-(4-(4-methoxyphenyl)-1H-1,2,3-triazol-1-yl)-3-methylpentan-2-yl)carbamate
There total 2 articles about tert-butyl ((2R,3S)-1-(4-(4-methoxyphenyl)-1H-1,2,3-triazol-1-yl)-3-methylpentan-2-yl)carbamate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium azide; copper; copper(II) sulfate; sodium L-ascorbate;
In
water; tert-butyl alcohol;
at 120 ℃;
for 0.333333h;
under 517.162 - 3102.97 Torr;
regioselective reaction;
Sealed tube;
Microwave irradiation;
DOI:10.1039/c2cc32392c
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: thionyl chloride / acetonitrile / 0.92 h / -40 °C / Inert atmosphere
1.2: -40 - 20 °C / Inert atmosphere
2.1: sodium periodate; ruthenium trichloride / water; acetonitrile / 0 °C
3.1: sodium azide; copper; copper(II) sulfate; sodium L-ascorbate / water; tert-butyl alcohol / 0.33 h / 120 °C / 517.16 - 3102.97 Torr / Sealed tube; Microwave irradiation
With
ruthenium trichloride; sodium periodate; thionyl chloride; sodium azide; copper; copper(II) sulfate; sodium L-ascorbate;
In
water; acetonitrile; tert-butyl alcohol;
DOI:10.1039/c2cc32392c