2,5-bisbenzhydrylthiophene

Base Information

• Chemical Name: 2,5-bisbenzhydrylthiophene
• CAS No.: 858848-88-1
• Molecular Formula: C₃₀H₂₄S
• Molecular Weight: 416.587
• Mol file: 858848-88-1.mol

Synonyms:2,5-bisbenzhydrylthiophene

Chemical Property of 2,5-bisbenzhydrylthiophene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5-bisbenzhydrylthiophene

There total 10 articles about 2,5-bisbenzhydrylthiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

thiophene (188290-36-0,8014-23-1,25233-34-5) + 1,1-Diphenylmethanol (91-01-0) → 2,5-bisbenzhydrylthiophene (858848-88-1)

Guidance literature:

With iron(III) chloride; In 1,2-dichloro-ethane; at 25 ℃; for 1h; Inert atmosphere;

DOI:10.1002/anie.201006779

Reference yield: 72.0%

thiophene (188290-36-0,8014-23-1,25233-34-5) + 2-benzhydryl-1,3-diphenylpropane-1,3-dione (60999-93-1) → 2,5-bisbenzhydrylthiophene (858848-88-1)

Guidance literature:

With iron(III) chloride; In 1,2-dichloro-ethane; at 25 ℃; for 1h; Inert atmosphere;

DOI:10.1002/anie.201006779

Reference yield: 55.0%

thiophene (188290-36-0,8014-23-1,25233-34-5) + Bromodiphenylmethane (776-74-9) → (2-thienyl)diphenylmethane (61532-53-4) + 2,5-bisbenzhydrylthiophene (858848-88-1)

Guidance literature:

With C₁₉H₁₀F₁₂S; In 1,2-dichloro-ethane; at 83 ℃; for 2h; Inert atmosphere; Molecular sieve;

DOI:10.1055/s-0033-1340343

upstream raw materials:

thiophene

1,1-Diphenylmethanol

ethyl diphenylmethyl ether

benzhydryl ether

Downstream raw materials:

benzophenone

2,5-dibenzhydryl-1,1-dioxo-1λ⁶-thiophene

Refernces

• 1、 Watanabe, Naruhisa,Matsugi, Aoi,Nakano, Keiji,Ichikawa, Yoshiyasu,Kotsuki, Hiyoshizo. "Organocatalytic friedel-crafts benzylation of heteroaromatic and aromatic compounds via an SN1 pathway". supporting information. p. 438 - 442. Retrieved 2014/03/21.