2-(benzoylamino)-N-cyclohexylbenzamide

Base Information

• Chemical Name: 2-(benzoylamino)-N-cyclohexylbenzamide
• CAS No.: 42103-84-4
• Molecular Formula: C₂₀H₂₂N₂O₂
• Molecular Weight: 322.407
• Mol file: 42103-84-4.mol

Synonyms:2-benzamido-N-cyclohexylbenzamide

Chemical Property of 2-(benzoylamino)-N-cyclohexylbenzamide

Chemical Property:

Purity/Quality:

2-(benzoylamino)-N-cyclohexylbenzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(benzoylamino)-N-cyclohexylbenzamide

There total 6 articles about 2-(benzoylamino)-N-cyclohexylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

Cyclohexyl isocyanide (931-53-3) + N-(2-bromophenyl)benzamide (70787-27-8) → 2-benzamido-N-cyclohexylbenzamide (42103-84-4)

Guidance literature:

With palladium diacetate; caesium carbonate; triphenylphosphine; In water; N,N-dimethyl-formamide; at 120 ℃; for 0.333333h; Sealed tube; Microwave irradiation;

DOI:10.24820/ark.5550190.p010.868

Reference yield: 62.0%

N-benzoylcyclohexylamine (1759-68-8) + 3-phenyl-5H-1,4,2-dioxazol-5-one (19226-36-9) → 2-benzamido-N-cyclohexylbenzamide (42103-84-4)

Guidance literature:

With silver hexafluoroantimonate; di-μ-chloro-bis[chloro(η⁵-pentamethylcyclopentadienyl)cobalt]; sodium acetate; In 1,2-dichloro-ethane; at 80 ℃; for 24h; under 760.051 Torr;

DOI:10.1002/anie.201505820

Reference yield:

2-phenyl-4H-3,1-benzoxazin-4-one (1022-46-4) + cyclohexylamine (108-91-8,157973-60-9) → 2-benzamido-N-cyclohexylbenzamide (42103-84-4) + 3-cyclohexyl-2-phenyl-3,4-dihydroquinazolin-4-one

Guidance literature:

With triphenyl phosphite; In pyridine; at 120 ℃;

DOI:10.1016/j.tetlet.2005.01.008

upstream raw materials:

2-phenyl-4H-3,1-benzoxazin-4-one

cyclohexylamine

anthranilic acid

N-benzoylcyclohexylamine

Refernces

• 1、 Park, Juhyeon,Chang, Sukbok. "Comparative Catalytic Activity of Group 9 [CpMIII] Complexes: Cobalt-Catalyzed C-H Amidation of Arenes with Dioxazolones as Amidating Reagents". supporting information. p. 14103 - 14107. Retrieved 2016/01/25.