GLUPHOSINAT

Base Information

• Chemical Name: GLUPHOSINAT
• CAS No.: 53369-07-6
• Molecular Formula: C5H12NO4P
• Molecular Weight: 181.13
• Mol file: 53369-07-6.mol

Synonyms:

Chemical Property of GLUPHOSINAT

Chemical Property:

• PSA: 110.43000
• LogP: 0.38890

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): Moderately toxic by ingestion.
• Hazard Codes: Moderately toxic by ingestion.

MSDS Files:

Useful:

Technology Process of GLUPHOSINAT

There total 75 articles about GLUPHOSINAT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-Chloroethyl <3-benzoylamino-3-(methoxycarbonyl)propyl>methylphosphinate (135265-34-8) → DL-homoalanin-4-yl(methyl)phosphinic acid (51276-47-2,53369-07-6)

Guidance literature:

With hydrogenchloride; Heating;

DOI:10.1246/bcsj.64.1707

Reference yield: 98.0%

C6H13N2O2P → DL-homoalanin-4-yl(methyl)phosphinic acid (51276-47-2,53369-07-6)

Guidance literature:

With hydrogenchloride; In water; for 2h; Reflux;

Reference yield: 96.7%

2-amino-4-(methylethoxyphosphoryl)butyronitrile → DL-homoalanin-4-yl(methyl)phosphinic acid (51276-47-2,53369-07-6)

Guidance literature:

With hydrogenchloride; In water; for 2h; Reflux;

upstream raw materials:

hydrogen cyanide

(3,3-Dimethoxy-propyl)-methyl-phosphinic acid ethyl ester

methyldiethoxyphosphine

ethyl methyl-(3,3-diethoxypropyl)phosphinate

Downstream raw materials:

L-phosphinothricin

4-[hydroxy(methyl)phosphonyl]-DL-homoalanine

Refernces

• 1、 -. "L-GLUFOSINATE INTERMEDIATE AND L-GLUFOSINATE PREPARATION METHOD". Paragraph 0160-0162. . Retrieved 2022/02/05.
• 2、 Cheng, Feng,Li, Ju-Mou,Zhou, Shi-Peng,Liu, Qi,Jin, Li-Qun,Xue, Ya-Ping,Zheng, Yu-Guo. "A Single-Transaminase-Catalyzed Biocatalytic Cascade for Efficient Asymmetric Synthesis of l-Phosphinothricin". . p. 345 - 348. Retrieved 2020/10/02.