Technology Process of 2,6-diaminopurine 2',3'-dideoxyriboside
There total 12 articles about 2,6-diaminopurine 2',3'-dideoxyriboside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
methanol;
atmospheric pressure;
- Guidance literature:
-
Multi-step reaction with 2 steps
2: 87 percent / H2 / 5percent Pd/C / ethanol / 20 h / 19 - 22 °C / 517.1 Torr
With
hydrogen;
palladium on activated charcoal;
In
ethanol;
DOI:10.1021/jo00129a034
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 90 percent / imidazole / dimethylformamide / 18 h / 20 °C
2: 96 percent / DMAP / acetonitrile / 1 h / 20 °C
3: 99 percent / (EtO)3P / 8 h / 100 - 115 °C
4: 81 percent / TBAF / tetrahydrofuran / 0.17 h / 0 °C
5: 47 percent / NH3 / methanol / 36 h / 90 °C
6: 99 percent / H2 / 10 percent Pd/C / methanol / atmospheric pressure
With
1H-imidazole; dmap; tetrabutyl ammonium fluoride; ammonia; hydrogen; triethyl phosphite;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide; acetonitrile;
