3-(methoxycarbonyl)-N,N,N-trimethylbenzenaminium iodide

Base Information

• Chemical Name: 3-(methoxycarbonyl)-N,N,N-trimethylbenzenaminium iodide
• CAS No.: 38803-34-8
• Molecular Formula: C₁₁H₁₆NO₂*I
• Molecular Weight: 321.158
• Mol file: 38803-34-8.mol

Synonyms:3-(methoxycarbonyl)-N,N,N-trimethylbenzenaminium iodide

Chemical Property of 3-(methoxycarbonyl)-N,N,N-trimethylbenzenaminium iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(methoxycarbonyl)-N,N,N-trimethylbenzenaminium iodide

There total 4 articles about 3-(methoxycarbonyl)-N,N,N-trimethylbenzenaminium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

3-(dimethylamino)benzoic acid methyl ester (16518-64-2) + methyl iodide (74-88-4) → 3-(methoxycarbonyl)-N,N,N-trimethylbenzenaminium iodide (38803-34-8)

Guidance literature:

In N,N-dimethyl-formamide; at 50 ℃; Inert atmosphere;

DOI:10.1021/jacs.1c04427

Reference yield: 65.0%

methanol (67-56-1) + 3-(dimethylamino)benzoic acid (99-64-9) + methyl iodide (74-88-4) → 3-(methoxycarbonyl)-N,N,N-trimethylbenzenaminium iodide (38803-34-8)

Guidance literature:

at 70 ℃; for 40h;

DOI:10.1016/j.molstruc.2012.02.051

Reference yield:

3-(dimethylamino)benzoic acid (99-64-9) → 3-(methoxycarbonyl)-N,N,N-trimethylbenzenaminium iodide (38803-34-8)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / water / Inert atmosphere; Reflux

2: N,N-dimethyl-formamide / 50 °C / Inert atmosphere

With hydrogenchloride; In water; N,N-dimethyl-formamide;

DOI:10.1021/jacs.1c04427

upstream raw materials:

3-(dimethylamino)benzoic acid methyl ester

methyl iodide

Methyl 3-aminobenzoate

methanol

Downstream raw materials:

3-(bromomethyl)-N,N-dimethylaniline

O²-(3-(dimethylamino)benzyl)-1-(N,N-diethylamino)-diazen-1-ium-1,2-diolate

benzoic acid methyl ester

3-dimethylaminobenzyl alcohol

Refernces

• 1、 Hendy, Cecilia M.,Smith, Gavin C.,Xu, Zihao,Lian, Tianquan,Jui, Nathan T.. "Radical Chain Reduction via Carbon Dioxide Radical Anion (CO2?-)". supporting information. p. 8987 - 8992. Retrieved 2021/07/01.