2,4,6-trimethoxybenzamide

Base Information

• Chemical Name: 2,4,6-trimethoxybenzamide
• CAS No.: 17483-54-4
• Molecular Formula: C₁₀H₁₃NO₄
• Molecular Weight: 211.218
• Mol file: 17483-54-4.mol

Synonyms:2,4,6-trimethoxybenzamide

Chemical Property of 2,4,6-trimethoxybenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4,6-trimethoxybenzamide

There total 3 articles about 2,4,6-trimethoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,6-trimethoxybenzoic acid (570-02-5) → 2,4,6-trimethoxybenzamide (17483-54-4)

Guidance literature:

2,4,6-trimethoxybenzoic acid; With trichlorophosphate; In dichloromethane; for 2h; Cooling with ice;

With ammonium hydroxide; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1007/s00044-021-02828-0

Reference yield:

1,2,3-trimethoxybenzene (621-23-8) → 2,4,6-trimethoxybenzamide (17483-54-4)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether

2: aq. KOH / Heating

With potassium hydroxide; In diethyl ether;

Reference yield:

2,4,6-Trimethoxy-N-chlorsulfonyl-benzamid (17483-30-6) → 2,4,6-trimethoxybenzamide (17483-54-4)

Guidance literature:

With potassium hydroxide; Heating;

upstream raw materials:

2,4,6-Trimethoxy-N-chlorsulfonyl-benzamid

1,2,3-trimethoxybenzene

2,4,6-trimethoxybenzoic acid

Downstream raw materials:

2,4,6-trimethoxyaniline hydrochloride

2,4,6-trimethoxyaniline

Refernces