Pentitol

Base Information

• Chemical Name: Pentitol
• CAS No.: 488-82-4
• Deprecated CAS: 12426-00-5,37191-59-6,7313-55-5,75398-81-1,84709-42-2
• Molecular Formula: C5H12O3
• Molecular Weight: 152.147
• Hs Code.: 29054980
• NSC Number: 83253,25288,25283,16868
• DSSTox Substance ID: DTXSID7042514
• Nikkaji Number: J1.453.993J
• Wikidata: Q81977867
• Metabolomics Workbench ID: 123381
• ChEMBL ID: CHEMBL1369426
• Mol file: 488-82-4.mol

Synonyms:(+--)-arabitol;arabinitol, D-;arabinitol, L-;arabino-pentitol;arabitol;arabitol, (D)-isomer;arabitol, (L)-isomer;D-arabinitol;D-arabitol;DL-arabitol;L-arabinitol;lyxitol

Chemical Property of Pentitol

Chemical Property:

• Appearance/Colour: white to off-white fine crystalline powder
• Vapor Pressure: 7.47E-12mmHg at 25°C
• Melting Point: 101-104 °C
• Refractive Index: 1.57
• Boiling Point: 494.5 °C at 760 mmHg
• PKA: 13.24±0.20(Predicted)
• Flash Point: 261.9 °C
• PSA: 101.15000
• Density: 1.525 g/cm³
• LogP: -2.94630
• Storage Temp.: Refrigerator (+4°C)
• Solubility.: H2O: 0.1 g/mL, clear, colorless
• Water Solubility.: Soluble in water (50 mg/ml).
• XLogP3: -2.5
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 152.06847348
• Heavy Atom Count: 10
• Complexity: 76.1

Purity/Quality:

98%, ^*data from raw suppliers

D-Arabinitol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 24/25-36-26

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C(C(C(CO)O)O)O)O
• Description: D-arabinitol is a characteristic metabolic product of candida species. While candida ssp. produces exclusively D-arabinitol, L-arabinitol is developed by the body’s own metabolism. D-arabinitol serum levels increase if candida yeasts proliferate within the organism and cause invasive Candidiasis. Both D-arabinitol and L-arabinitol are present in normal urine, and can easily be measured by gas chromatography of urine samples collected on filter paper.
• Uses: D-Arabitol, a rare sugar alcohol, is a substrate used to identify, differentiate and characterize enzyme such as the gluconobacter oxydans dehydrogenase(s), Gox2181, hyperthermophilic D-arabitol dehydrogenase from Thermotoga maritime and NAD-dependent D-arabitoldehydrogenase from acetic acid bacterium, Acetobacter suboxydans.

Technology Process of Pentitol

There total 117 articles about Pentitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.97%

D-xylose (58-86-6) → D-Arabitol (488-82-4) + XYLITOL (87-99-0)

Guidance literature:

With hydrogen; Ni_6.66Fe₁Al_1.55; In water; at 180 ℃; for 0.5h; under 22502.3 Torr; Temperature; High pressure;

DOI:10.1002/cjoc.202100140

Reference yield: 66.0%

D-Arabinose (10323-20-3) → D-Arabitol (488-82-4) + XYLITOL (87-99-0)

Guidance literature:

With Butane-1,4-diol; Cu₃Ni₃Al₂; In water; at 149.84 ℃; pH=9 - 10;

DOI:10.1002/cctc.201403005

Reference yield:

α-cellulose → 1,4-sorbitan (20662-31-1) + β-D-glucose (492-61-5) + 1,2,3,4,5-pentahydroxy-pentane (87-99-0,488-81-3,488-82-4,2152-56-9,6917-36-8,7643-75-6) + sorbitol (50-70-4,69-65-8,87-78-5,133-43-7,488-44-8,488-45-9,608-66-2,643-01-6,643-03-8,5552-13-6,6706-59-8,24557-79-7,25878-23-3,26566-34-7,45007-61-2,60660-56-2,60660-57-3,60660-58-4,132747-27-4)

Guidance literature:

With sulfuric acid; 5% active carbon-supported ruthenium; water; hydrogen; tungsten; at 159.84 ℃; for 1h; under 37503.8 Torr; Autoclave;

DOI:10.1039/c0cc02263b

upstream raw materials:

D-Arabinose

D-lyxose

D-Glucose

D-2-deoxyglucose

Downstream raw materials:

pentakis-O-(2,4-dinitro-phenyl)-D-arabitol

1,3-O-benzylidene D-arabitol

1.5-dibenzoyloxy-D-arabino-pentanetriol-(2.3.4)

1,5-Bis-O-(p-tolylsulfonyl)-D-arabit

Refernces

• 1、 Lin, Lu,Qiu, Jiarong,Sun, Yong,Tang, Xing,Zeng, Xianhai,Zhang, Liangqing. "Efficient Synthesis of Sugar Alcohols over a Synergistic and Sustainable Catalyst". . p. 2467 - 2476. Retrieved 2021.
• 2、 Mishra, Dinesh Kumar,Dabbawala, Aasif Asharaf,Hwang, Jin-Soo. "Ruthenium nanoparticles supported on zeolite y as an efficient catalyst for selective hydrogenation of xylose to xylitol". . p. 63 - 70. Retrieved 2013.
• 3、 Nemec,Jary. "". . p. 1222. Retrieved 1968.
• 4、 Gumina, Bianca,Mauriello, Francesco,Pietropaolo, Rosario,Galvagno, Signorino,Espro, Claudia. "Hydrogenolysis of sorbitol into valuable C3-C2 alcohols at low H2 pressure promoted by the heterogeneous Pd/Fe3O4 catalyst". . p. 152 - 160. Retrieved 2018/02/17.