2,2',5,5'-Tetrachlorobenzidine

Base Information

• Chemical Name: 2,2',5,5'-Tetrachlorobenzidine
• CAS No.: 15721-02-5
• Molecular Formula: C12H8Cl4N2
• Molecular Weight: 322.021
• Hs Code.: 2921590090
• European Community (EC) Number: 239-815-3
• UNII: ICS5PD3141
• DSSTox Substance ID: DTXSID7021314
• Nikkaji Number: J35.599B
• Wikidata: Q27156051
• ChEMBL ID: CHEMBL3186078
• Mol file: 15721-02-5.mol

Synonyms:2,2',5,5'-tetrachlorobenzidine;2,2'5,5'-TCB

Chemical Property of 2,2',5,5'-Tetrachlorobenzidine

Chemical Property:

• Melting Point: 135-140 °C(lit.)
• Refractive Index: 1.6000 (estimate)
• Boiling Point: 408.196 °C at 760 mmHg
• PKA: 1.58±0.13(Predicted)
• Flash Point: 200.67 °C
• PSA: 52.04000
• Density: 1.555 g/cm³
• LogP: 6.29400
• Storage Temp.: -70°C
• Solubility.: soluble in Methanol
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 321.941209
• Heavy Atom Count: 18
• Complexity: 263

Purity/Quality:

98%, ^*data from raw suppliers

2,2'',5,5''-Tetrachlorobenzidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 61
• Safety Statements: 53-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=CC(=C1Cl)N)Cl)C2=CC(=C(C=C2Cl)N)Cl

Technology Process of 2,2',5,5'-Tetrachlorobenzidine

There total 4 articles about 2,2',5,5'-Tetrachlorobenzidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N'-bis-(2,5-dichloro-phenyl)-hydrazine (60696-76-6) → 2,2',5,5'-tetrachloro-4,4'-diaminobiphenyl (15721-02-5)

Guidance literature:

With hydrogenchloride;

Reference yield:

2,5-dichloro-4-aminoacetanilide (6392-96-7) → 2,2',5,5'-tetrachloro-4,4'-diaminobiphenyl (15721-02-5)

Guidance literature:

With hydrogenchloride; sodium nitrite; Behandeln der bereiteten Diazoniumsalz-Loesung mit Kupfer-Pulver und Erhitzen des Reaktionsprodukts mit wss.Schwefelsaeure;

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + 2,5-dichloro-4-aminoacetanilide (6392-96-7) → 2,2',5,5'-tetrachloro-4,4'-diaminobiphenyl (15721-02-5)

Guidance literature:

Erwaermen der Reaktionsloesung mit Kupfer-Pulver und Erhitzen des Reaktionsprodukts mit wss.Schwefelsaeure;

upstream raw materials:

N,N'-bis-(2,5-dichloro-phenyl)-hydrazine

2,5-dichloro-4-aminoacetanilide

hydrogenchloride

Downstream raw materials:

2,2',3,3',5,5'-hexachlorobiphenyl

2,2',5,5'-Tetrachlorobiphenyl

2,2',4,4',5,5'-Hexachlorobiphenyl

Refernces

• 1、 -. "One step diazotization coupling process". . . Retrieved 2008/06/13.