4-(2-Dimethoxymethyl-butyl)-benzoic acid ethyl ester

Base Information

• Chemical Name: 4-(2-Dimethoxymethyl-butyl)-benzoic acid ethyl ester
• CAS No.: 159691-44-8
• Molecular Formula: C₁₆H₂₄O₄
• Molecular Weight: 280.364
• Mol file: 159691-44-8.mol

Synonyms:4-(2-Dimethoxymethyl-butyl)-benzoic acid ethyl ester

Chemical Property of 4-(2-Dimethoxymethyl-butyl)-benzoic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 4-(2-Dimethoxymethyl-butyl)-benzoic acid ethyl ester

There total 1 articles about 4-(2-Dimethoxymethyl-butyl)-benzoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + ethyl 4-(3'-oxo-2'-ethylprop-1'-yl)benzoate (159691-43-7) → 4-(2-Dimethoxymethyl-butyl)-benzoic acid ethyl ester (159691-44-8)

Guidance literature:

With camphor-10-sulfonic acid; trimethyl orthoformate; at 37 ℃; for 3h;

DOI:10.1021/ja00104a008

Reference yield:

4-(2-Dimethoxymethyl-butyl)-benzoic acid ethyl ester (159691-44-8) → 4-{2-[1-Methoxy-meth-(E)-ylidene]-butyl}-benzoic acid ethyl ester

Guidance literature:

With iodotrimethyldisilane; 1,1,1,3,3,3-hexamethyl-disilazane; In tetrachloromethane; at 60 ℃; for 5h;

DOI:10.1021/ja00104a008

Reference yield:

4-(2-Dimethoxymethyl-butyl)-benzoic acid ethyl ester (159691-44-8) → (Z)-N-(hydroxyethyl)-4-(3'-methoxy-2'-ethyl-2'-propen-1'-yl)benzamide (159691-42-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 mg / hexamethyldisilazane, iodotrimethyldisilane / CCl₄ / 5 h / 60 °C

2: 45 mg / 50 °C

With iodotrimethyldisilane; 1,1,1,3,3,3-hexamethyl-disilazane; In tetrachloromethane;

DOI:10.1021/ja00104a008

upstream raw materials:

methanol

ethyl 4-(3'-oxo-2'-ethylprop-1'-yl)benzoate

Downstream raw materials:

(Z)-N-(hydroxyethyl)-4-(3'-methoxy-2'-ethyl-2'-propen-1'-yl)benzamide

(E)-N-(hydroxyethyl)-4-(3'-methoxy-2'-ethyl-2'-propen-1'-yl)benzamide

Refernces