3,4-Dibromofuran-2(5H)-one

Base Information

• Chemical Name: 3,4-Dibromofuran-2(5H)-one
• CAS No.: 149418-41-7
• Molecular Formula: C4H2 Br2 O2
• Molecular Weight: 241.867
• Hs Code.: 2932209090
• European Community (EC) Number: 686-996-3
• DSSTox Substance ID: DTXSID30164265
• Nikkaji Number: J1.453.568C
• Wikidata: Q83033322
• Mol file: 149418-41-7.mol

Synonyms:3,4-Dibromofuran-2(5H)-one;149418-41-7;3,4-dibromo-2H-furan-5-one;3,4-Dibromo-2(5H)-furanone;2(5H)-Furanone, 3,4-dibromo-;3,4-dibromo-5H-furan-2-one;CCRIS 6705;3,4-Dibromo-2,5-dihydrofuran-2-one;SCHEMBL1558716;2,3-dibromo-2-buten-4-olide;3,4-dibromo-2(5H) furanone;DTXSID30164265;UBAYSWXSWXORAN-UHFFFAOYSA-N;ZFA41841;MFCD02752391;AKOS015834431;SB61798;3,4-Dibromo-2(5H)-furanone, 97%;AS-54907;CS-0092876;FT-0685414;EN300-75643;W10946;A884277;W-205689

Chemical Property of 3,4-Dibromofuran-2(5H)-one

Chemical Property:

• Vapor Pressure: 0.000449mmHg at 25°C
• Melting Point: 90-94°C
• Boiling Point: 315°C at 760 mmHg
• Flash Point: 144.3°C
• PSA: 26.30000
• Density: 2.566g/cm³
• LogP: 1.54460
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 241.84011
• Heavy Atom Count: 8
• Complexity: 161

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,4-Dibromofuran-2(5h)-one ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1C(=C(C(=O)O1)Br)Br

Technology Process of 3,4-Dibromofuran-2(5H)-one

There total 13 articles about 3,4-Dibromofuran-2(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

mucobromic acid (766-38-1) → 3,4-dibromo-2(5H)-furanone (149418-41-7)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 ℃;

DOI:10.1590/S0103-50532011000300026

Reference yield:

C4H4Br2O3 → 3,4-dibromo-2(5H)-furanone (149418-41-7)

Guidance literature:

With sulfuric acid; In methanol; at 0 ℃; Inert atmosphere;

DOI:10.1002/cbdv.201400416

Reference yield:

mucobromic acid (488-11-9) → 3,4-dibromo-2(5H)-furanone (149418-41-7)

Guidance literature:

mucobromic acid; With sodium tetrahydroborate; In methanol; at -2 ℃; for 0.25h;

With sulfuric acid; at -2 ℃; for 0.5h;

DOI:10.1111/j.1747-0285.2012.01342.x

upstream raw materials:

mucobromic acid

3,4-dibromo-furan-2-carboxylic acid

α.β-dibromo-γ-oxy-crotonic acid

Trans-2,3-dibromo-2-butene-1,4-diol

Downstream raw materials:

4-anilino-3-bromo-5H-furan-2-one

mucobromic acid

dibromomaleic acid

biphenyl

Refernces

• 1、 Pereira, Ulisses A.,Barbosa, Luiz C. A.,Demuner, Ant?nio J.,Silva, Ant?nio A.,Bertazzini, Michele,Forlani, Giuseppe. "Rubrolides as Model for the Development of New Lactones and Their Aza Analogs as Potential Photosynthesis Inhibitors". . p. 987 - 1006. Retrieved 2015.
• 2、 Pereira, Ulisses A.,Barbosa, Luiz C.A.,Maltha, Célia R.A.,Demuner, Ant?nio J.,Masood, Mohammed A.,Pimenta, Andréa L.. "Inhibition of Enterococcus faecalis biofilm formation by highly active lactones and lactams analogues of rubrolides". . p. 127 - 138. Retrieved 2014/06/23.