Technology Process of 2-(3-Benzyloxy-propyl)-3,6-diethoxy-2,5-dihydro-pyrazine
There total 1 articles about 2-(3-Benzyloxy-propyl)-3,6-diethoxy-2,5-dihydro-pyrazine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 1.) 10percent HCl; 2.) sodium borohydride
2: 91 percent / NaOEt
3: 89 percent / DMAP, TEA
4: 95 percent / hydrogen / 10percent Pd/C
5: 86 percent / Swern oxidation
6: 64 percent / potassium hexamethyldisilazide / tetrahydrofuran / -78 °C
7: 80 percent / 70percent acetic acid / Heating
8: 85 percent / p-toluenesulfonic acid / toluene / Heating
With
hydrogenchloride; dmap; sodium tetrahydroborate; TEA; hydrogen; sodium ethanolate; potassium hexamethylsilazane; toluene-4-sulfonic acid; acetic acid;
palladium on activated charcoal;
In
tetrahydrofuran; toluene;
DOI:10.1016/0040-4039(96)00499-6
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 1.) 10percent HCl; 2.) sodium borohydride
2: 91 percent / NaOEt
3: 89 percent / DMAP, TEA
4: 95 percent / hydrogen / 10percent Pd/C
5: 86 percent / Swern oxidation
6: 64 percent / potassium hexamethyldisilazide / tetrahydrofuran / -78 °C
7: 80 percent / 70percent acetic acid / Heating
With
hydrogenchloride; dmap; sodium tetrahydroborate; TEA; hydrogen; sodium ethanolate; potassium hexamethylsilazane; acetic acid;
palladium on activated charcoal;
In
tetrahydrofuran;
DOI:10.1016/0040-4039(96)00499-6