1,2-Dichloro-3-(dimethylamino)propane hydrochloride

Base Information

• Chemical Name: 1,2-Dichloro-3-(dimethylamino)propane hydrochloride
• CAS No.: 50786-84-0
• Molecular Formula: C5H11 Cl2 N . Cl H
• Molecular Weight: 192.516
• Hs Code.: 2921199090
• NSC Number: 150231
• Mol file: 50786-84-0.mol

Synonyms:50786-84-0;1,2-Dichloro-3-(dimethylamino)propane hydrochloride;NSC 150231;2,3-Dichloro-N,N-dimethyl-1-propylamine hydrochloride;1-Dimethylamino-2,3-dichloropropane hydrochloride;Propylamine, 2,3-dichloro-N,N-dimethyl-, hydrochloride;1-Propanamine, 2,3-dichloro-N,N-dimethyl-, hydrochloride;1-Propylamine, 2,3-dichloro-N,N-dimethyl-, hydrochloride;N,N-DIMETHYL-2,3-DICHLORO-1-PROPANAMINE HYDROCHLORIDE;C(Cl)(CCl)CN(C)C;NSC150231;NSC-150231;LS-125598;Propylamine,3-dichloro-N,N-dimethyl-, hydrochloride;1-Propanamine,3-dichloro-N,N-dimethyl-, hydrochloride;2,3-dichloro-N,N-dimethylpropan-1-amine;hydrochloride

Chemical Property of 1,2-Dichloro-3-(dimethylamino)propane hydrochloride

Chemical Property:

• Vapor Pressure: 6.87mmHg at 25°C
• Melting Point: 165-167 °C(Solv: acetone (67-64-1); methanol (67-56-1))
• Boiling Point: 138°C at 760 mmHg
• Flash Point: 37.2°C
• PSA: 3.24000
• Density: 1.103g/cm³
• LogP: 2.19620
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 191.003532
• Heavy Atom Count: 9
• Complexity: 56.4

Purity/Quality:

99% ^*data from raw suppliers

N,N-DIMETHYL-2,3-DICHLORO-1-PROPANAMINE HCL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CC(CCl)Cl.Cl

Technology Process of 1,2-Dichloro-3-(dimethylamino)propane hydrochloride

There total 1 articles about 1,2-Dichloro-3-(dimethylamino)propane hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-dimethyl-2-propen-1-amine (2155-94-4) → 1-(N,N-dimethylamino)-2,3-dichloropropane hydrochloride (50786-84-0)

Guidance literature:

With hydrogenchloride; chlorine; Yield given. Multistep reaction; CHCl₃, 1) 0 deg C;

Reference yield:

1-thiopropane (107-03-9) + 1-(N,N-dimethylamino)-2,3-dichloropropane hydrochloride (50786-84-0) → nereistoxin (1631-58-9) + Dimethyl-(2-propyldisulfanyl-1-propyldisulfanylmethyl-ethyl)-amine (3950-63-8) + [2-(2-Dimethylamino-3-propyldisulfanyl-propyldisulfanyl)-1-propyldisulfanylmethyl-ethyl]-dimethyl-amine + Dipropyl disulfide (629-19-6)

Guidance literature:

With sodium hydroxide; sodium thiosulfate; sodium chloride; Yield given. Multistep reaction. Yields of byproduct given; 1) EtOH, H₂O, reflux, 30 min., 2) H₂O, CHCl₃, 3 h;

Reference yield:

1-methyl-1-propanethiol (513-53-1,91840-99-2) + 1-(N,N-dimethylamino)-2,3-dichloropropane hydrochloride (50786-84-0) → nereistoxin (1631-58-9) + sec-butyl disulfide (5943-30-6) + (2-sec-Butyldisulfanyl-1-sec-butyldisulfanylmethyl-ethyl)-dimethyl-amine + [2-sec-Butyldisulfanyl-1-(3-sec-butyldisulfanyl-2-dimethylamino-propyldisulfanylmethyl)-ethyl]-dimethyl-amine

Guidance literature:

With sodium hydroxide; sodium thiosulfate; sodium chloride; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given; 1) EtOH, H₂O, reflux, 30 min., 2) H₂O, CHCl₃, 5 h;

upstream raw materials:

N,N-dimethyl-2-propen-1-amine

Downstream raw materials:

nereistoxin

Dimethyl-(2-propyldisulfanyl-1-propyldisulfanylmethyl-ethyl)-amine

5-dimethylamino-1,2,3-trithiane

Dipropyl disulfide

Refernces