Methyltrienolone

Base Information

• Chemical Name: Methyltrienolone
• CAS No.: 965-93-5
• Molecular Formula: C₁₉H₂₄O₂
• Molecular Weight: 284.398
• Hs Code.: 29061900
• European Community (EC) Number: 663-842-3
• NSC Number: 92858
• UNII: 2C323EGI97
• DSSTox Substance ID: DTXSID8034162
• Nikkaji Number: J134.074C
• Wikipedia: Metribolone
• Wikidata: Q3333717
• NCI Thesaurus Code: C166564
• Pharos Ligand ID: 9CAN1V7K38JF
• Metabolomics Workbench ID: 52753
• ChEMBL ID: CHEMBL166444
• Mol file: 965-93-5.mol

Synonyms:17 beta-Hydroxy-17 alpha-methylestra-4,9,11-trien-3-one;Methyltrienolone;Metribolone;R 1881;R-1881;R1881;Ru 1881;Ru-1881;Ru1881

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Methyltrienolone

Chemical Property:

• Vapor Pressure: 1.76E-11mmHg at 25°C
• Melting Point: 206-209°C
• Refractive Index: 1.597
• Boiling Point: 485.9 °C at 760 mmHg
• PKA: 14.79±0.40(Predicted)
• Flash Point: 206.3 °C
• PSA: 37.30000
• Density: 1.17 g/cm³
• LogP: 3.71940
• Storage Temp.: 2-8°C
• Solubility.: DMSO: ≥10mg/mL
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 284.177630004
• Heavy Atom Count: 21
• Complexity: 609

Purity/Quality:

Safty Information:

• Pictogram(s): F,Xi
• Hazard Codes: F,Xi

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1(CCC2C1(C=CC3=C4CCC(=O)C=C4CCC23)C)O
• Isomeric SMILES: C[C@@]1(CC[C@@H]2[C@@]1(C=CC3=C4CCC(=O)C=C4CC[C@@H]23)C)O
• Description: Methyltrienolone is an orally active anabolic-androgen steroid being a 17α-alkylated nandrolone (19-nortestosterone) derivative. It is not sold as a prescription drug and a dietary supplement due to its strong androgenic side effects and liver toxicity. However, it is often used as the reference point for in vitro biological activity for biochemical studies. It can bind strongly to the androgen receptor and can be used as an affinity label of the androgen receptor in the prostate and in prostatic tumors.

Technology Process of Methyltrienolone

There total 4 articles about Methyltrienolone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 17α-Methyl-17β-hydroxy-Δ4,9,11-oestratrien-3-on (965-93-5,10110-87-9)

Guidance literature:

Oxim IV, AcOH, AcCO2H;

Reference yield:

→ 3-Oxo-17α-methyl-17β-hydroxyestra-4,9,11-trien (965-93-5,10110-87-9)

Guidance literature:

11β-Hydroxyverb., HClO4;

Reference yield:

→ 17β-Methyl-4.9.11-estratrien-17α-ol-3-on (965-93-5,10110-87-9)

Guidance literature:

aus 17β-Methyl-5(10).9(11)-estradien-17α-ol-3-on u. 2.3-Dichlor-5.6-dicyano-p-benzochinon (II);