1,3-bis[4-(3-aminopropyloxy)-2,6-diisopropylphenyl]imidazolium iodide

Base Information

• Chemical Name: 1,3-bis[4-(3-aminopropyloxy)-2,6-diisopropylphenyl]imidazolium iodide
• CAS No.: 1620922-85-1
• Molecular Formula: C₃₃H₅₁N₄O₂*I
• Molecular Weight: 662.698
• Mol file: 1620922-85-1.mol

Synonyms:1,3-bis[4-(3-aminopropyloxy)-2,6-diisopropylphenyl]imidazolium iodide

Chemical Property of 1,3-bis[4-(3-aminopropyloxy)-2,6-diisopropylphenyl]imidazolium iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-bis[4-(3-aminopropyloxy)-2,6-diisopropylphenyl]imidazolium iodide

There total 7 articles about 1,3-bis[4-(3-aminopropyloxy)-2,6-diisopropylphenyl]imidazolium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1,3-bis(4-{3-[(tert-butoxycarbonyl)amino]propyloxy}-2,6-diisopropylphenyl)imidazolium iodide (1620922-84-0) → 1,3-bis[4-(3-aminopropyloxy)-2,6-diisopropylphenyl]imidazolium iodide (1620922-85-1)

Guidance literature:

With acetyl chloride; In ethanol; at 20 ℃; for 7h; Inert atmosphere; Schlenk technique;

DOI:10.1002/adsc.201300903

Reference yield:

2,6-diisopropylbenzenamine (24544-04-5) → 1,3-bis[4-(3-aminopropyloxy)-2,6-diisopropylphenyl]imidazolium iodide (1620922-85-1)

Guidance literature:

Multi-step reaction with 7 steps

1.1: potassium iodide; tert.-butylhydroperoxide / acetonitrile; water / 6.25 h / 70 °C

2.1: ammonium chloride / acetone / 0.5 h / Inert atmosphere; Schlenk technique

2.2: 5 h / Inert atmosphere; Schlenk technique

3.1: sulfuric acid / water; diethyl ether / 12.17 h / Inert atmosphere; Schlenk technique

4.1: formic acid / ethanol / 8 h / Inert atmosphere; Schlenk technique; Heating

5.1: dimethyl sulfoxide / 48 h / 45 - 50 °C / Inert atmosphere; Schlenk technique

6.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 80 °C / Inert atmosphere; Schlenk technique

7.1: acetyl chloride / ethanol / 7 h / 20 °C / Inert atmosphere; Schlenk technique

With tert.-butylhydroperoxide; formic acid; sulfuric acid; potassium carbonate; ammonium chloride; acetyl chloride; potassium iodide; In diethyl ether; ethanol; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone; acetonitrile;

DOI:10.1002/adsc.201300903

Reference yield:

1,3-bis(2,6-diisopropyl-4-hydroxyphenyl)imidazolium chloride (1620922-83-9) → 1,3-bis[4-(3-aminopropyloxy)-2,6-diisopropylphenyl]imidazolium iodide (1620922-85-1)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 80 °C / Inert atmosphere; Schlenk technique

2: acetyl chloride / ethanol / 7 h / 20 °C / Inert atmosphere; Schlenk technique

With potassium carbonate; acetyl chloride; In ethanol; N,N-dimethyl-formamide;

DOI:10.1002/adsc.201300903

upstream raw materials:

1,3-bis(2,6-diisopropyl-4-hydroxyphenyl)imidazolium chloride

2,6-diisopropylbenzenamine

1,3-bis(4-{3-[(tert-butoxycarbonyl)amino]propyloxy}-2,6-diisopropylphenyl)imidazolium iodide

1,3-diisopropyl-2-nitrobenzene

Refernces