Fertilysin

Base Information

• Chemical Name: Fertilysin
• CAS No.: 1477-57-2
• Molecular Formula: C12H20 Cl4 N2 O2
• Molecular Weight: 366.115
• Hs Code.: 2924199090
• European Community (EC) Number: 216-033-0
• NSC Number: 59354
• UNII: 3F56RA64JN
• DSSTox Substance ID: DTXSID80163783
• Nikkaji Number: J1.769H
• Wikidata: Q27162547
• Pharos Ligand ID: P3BDNCW5BKZ2
• ChEMBL ID: CHEMBL3276621
• Mol file: 1477-57-2.mol

Synonyms:bis-diamine;N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine;Win 18446;Win-18446

Chemical Property of Fertilysin

Chemical Property:

• Melting Point: 118-120 °C
• Refractive Index: 1.6200 (estimate)
• Boiling Point: 530.2°Cat760mmHg
• PKA: 12.28±0.46(Predicted)
• Flash Point: 274.5°C
• PSA: 58.20000
• Density: 1.285g/cm³
• LogP: 3.94860
• Storage Temp.: 2-8°C
• Solubility.: Acetone (Very Slightly), DMSO (Slightly), Methanol (Sparingly, Heated, Sonicated
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 11
• Exact Mass: 366.024939
• Heavy Atom Count: 20
• Complexity: 261

Purity/Quality:

98%min ^*data from raw suppliers

WIN 18446 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-40
• Safety Statements: 24/25-45-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCCCNC(=O)C(Cl)Cl)CCCNC(=O)C(Cl)Cl
• Uses: Win 18446 was shown to inhibit the biosynthesis of retinoic acid from retinol in neonatal and adult murine testis and in the embryonic murine gonad.

Technology Process of Fertilysin

There total 2 articles about Fertilysin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dichloroacethyl chloride (79-36-7) + 1,8-diaminooctan (373-44-4) → N,N'-(octane-1,8-diyl)bis(2,2-dichloroacetamide) (1477-57-2)

Guidance literature:

DOI:10.1021/jm50016a002

Reference yield:

→ N,N'-(octane-1,8-diyl)bis(2,2-dichloroacetamide) (1477-57-2)

Guidance literature:

Diamin (I, R=R': H, n=8), Cl2CH-COCl;

upstream raw materials:

dichloroacethyl chloride

1,8-diaminooctan