2,3-dimethyl-6-nitroanisole

Base Information

• Chemical Name: 2,3-dimethyl-6-nitroanisole
• CAS No.: 99321-71-8
• Molecular Formula: C₉H₁₁NO₃
• Molecular Weight: 181.191
• Mol file: 99321-71-8.mol

Synonyms:2,3-dimethyl-6-nitroanisole

Chemical Property of 2,3-dimethyl-6-nitroanisole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-dimethyl-6-nitroanisole

There total 6 articles about 2,3-dimethyl-6-nitroanisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

5,6-dimethyl-2,6-dinitrocyclohexa-2,4-dienyl methyl ether (99321-70-7) → 4-nitro-o-xylene (99-51-4,34527-23-6,156617-88-8) + 2,3-dimethyl-6-nitroanisole (99321-71-8)

Guidance literature:

With boron trifluoride diethyl etherate; at 0 ℃; for 1.2h;

Reference yield:

4-nitro-o-xylene (99-51-4,34527-23-6,156617-88-8) → 2,3-dimethyl-6-nitroanisole (99321-71-8)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium bromide / 48 h / 0 °C

2: 23 percent / methanol

3: 42 percent / boron trifluoride-etherate / 1.2 h / 0 °C

With boron trifluoride diethyl etherate; potassium bromide; In methanol;

Reference yield:

5,6-dimethyl-2,6-dinitrocyclohexa-2,4-dienyl acetate (99321-75-2) → 2,3-dimethyl-6-nitroanisole (99321-71-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 23 percent / methanol

2: 42 percent / boron trifluoride-etherate / 1.2 h / 0 °C

With boron trifluoride diethyl etherate; In methanol;

upstream raw materials:

2,3-dimethyl-6-nitrophenol

diazomethane

dimethyl sulfate

5,6-dimethyl-2,6-dinitrocyclohexa-2,4-dienyl methyl ether

Downstream raw materials:

2-methoxy-3,4-dimethylphenol

2-methoxy-3.4-dimethylaniline

Refernces

• 1、 Fischer, Alfred,Henderson, George N.,Iyer, Lokanathan M.. "ipso Nitration. XXVI. Nitration of 1,2-dimethyl-4-nitrobenzene. Formation and reactions of adducts". . p. 2390 - 2400. Retrieved 2007/10/02.