Cefmenoxime Hydrochloride

Base Information

• Chemical Name: Cefmenoxime Hydrochloride
• CAS No.: 75738-58-8
• Molecular Formula: C32H35ClN18O10S6
• Molecular Weight: 529.77
• Hs Code.: 2941906000
• European Community (EC) Number: 278-299-4
• UNII: NON736D32W
• ChEMBL ID: CHEMBL3183193
• DSSTox Substance ID: DTXSID0046646
• NCI Thesaurus Code: C65296
• Mol file: 75738-58-8.mol

Synonyms:Abbott 50192;Abbott-50192;Abbott50192;Cefmax;Cefmenoxime;Cefmenoxime Hydrochloride;Cefmenoxime Hydrochloride (2:1);Hydrochloride, Cefmenoxime;SCE 1365;SCE-1365;SCE1365

Chemical Property of Cefmenoxime Hydrochloride

Chemical Property:

• PSA: 269.65000
• LogP: 0.04020
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility.: DMSO (Slightly, Heated), Methanol (Slightly)
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 28
• Rotatable Bond Count: 16
• Exact Mass: 1058.0796341
• Heavy Atom Count: 67
• Complexity: 890

Purity/Quality:

99% ^*data from raw suppliers

CefmenoximeHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O.CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O.Cl
• Isomeric SMILES: CN1N=NN=C1SCC2=C(N3C(=O)[C@H]([C@H]3SC2)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)C(=O)O.CN1N=NN=C1SCC2=C(N3C(=O)[C@H]([C@H]3SC2)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)C(=O)O.Cl
• Recent NIPH Clinical Trials: Effects of topical antibiotics after intravitreal injection of anti-vascular endothelial growth factor
• Description: Cef menoxime hydrochloride is a third generation cephalosporin antibiotic. Structurally, it possesses the (1-methyl-lH-tetrazol-5-yl)thiomethyl moiety in the 3-position; like several other compounds containing this structural element (moxalactam, cefoperazone, cefamandol), bleeding linked to vitamin K interaction has been reported. Cefmenoxime has activity similar to cefotiuime, ceftizoxime and moxalactam against E.coli, C. diversus, Klebsiella, P. Mirabilis, Salmonella, Shigella, Neiseria spp., S. pyogenes, S. Pneumoniae, and g. influenzae. It is relatively ineffective against Pseudomonas and Bacteroidea.
• Uses: A third generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis. antibacterial