N²-<(2-nitrophenyl)thio>oxamniquine aldehyde

Base Information

• Chemical Name: N²-<(2-nitrophenyl)thio>oxamniquine aldehyde
• CAS No.: 114719-26-5
• Molecular Formula: C₂₀H₂₂N₄O₅S
• Molecular Weight: 430.484
• Mol file: 114719-26-5.mol

Synonyms:N²-<(2-nitrophenyl)thio>oxamniquine aldehyde

Chemical Property of N²-<(2-nitrophenyl)thio>oxamniquine aldehyde

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of N²-<(2-nitrophenyl)thio>oxamniquine aldehyde

There total 2 articles about N²-<(2-nitrophenyl)thio>oxamniquine aldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

oxamniquine aldehyde (53503-66-5) + 2-nitrobenzenesulfenyl chloride (7669-54-7) → N2-<(2-nitrophenyl)thio>oxamniquine aldehyde (114719-26-5)

Guidance literature:

With triethylamine; In dichloromethane; for 1h; Ambient temperature;

DOI:10.1021/jm00403a024

Reference yield:

oxaminiquine (21738-42-1,40247-39-0,119678-90-9) → N2-<(2-nitrophenyl)thio>oxamniquine aldehyde (114719-26-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / MnO₂ / CH₂Cl₂

2: 90 percent / triethylamine / CH₂Cl₂ / 1 h / Ambient temperature

With manganese(IV) oxide; triethylamine; In dichloromethane;

DOI:10.1021/jm00403a024

Reference yield: 95.0%

N2-<(2-nitrophenyl)thio>oxamniquine aldehyde (114719-26-5) → N2-<(2-nitrophenyl)thio>oxamniquine (114719-27-6)

Guidance literature:

With sodium tetrahydroborate; In methanol; dichloromethane; for 2h; Ambient temperature;

DOI:10.1021/jm00403a024

upstream raw materials:

oxamniquine aldehyde

2-nitrobenzenesulfenyl chloride

oxaminiquine

Downstream raw materials:

N²-<(2-nitrophenyl)thio>oxamniquine

Acetic acid 2-{[isopropyl-(2-nitro-phenylsulfanyl)-amino]-methyl}-7-nitro-1,2,3,4-tetrahydro-quinolin-6-ylmethyl ester

N²-<(2-nitrophenyl)thio>oxamniquine N-methylcarbamate

Refernces