α-p-Nitro-benzyl-γ-methyl-L-glutamat

Base Information

• Chemical Name: α-p-Nitro-benzyl-γ-methyl-L-glutamat
• CAS No.: 96789-24-1
• Molecular Formula: C₁₃H₁₆N₂O₆
• Molecular Weight: 296.28
• Mol file: 96789-24-1.mol

Synonyms:α-p-Nitro-benzyl-γ-methyl-L-glutamat

Chemical Property of α-p-Nitro-benzyl-γ-methyl-L-glutamat

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-p-Nitro-benzyl-γ-methyl-L-glutamat

There total 3 articles about α-p-Nitro-benzyl-γ-methyl-L-glutamat which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-Carbobenzoxy-<α-p-nitro-benzyl,γ-methyl>-L-glutamat (910908-63-3) → α-p-Nitro-benzyl-γ-methyl-L-glutamat (96789-24-1)

Guidance literature:

With hydrogen bromide; In acetic acid;

DOI:10.1246/bcsj.37.200

Reference yield:

(S)-2-Benzyloxycarbonylamino-pentanedioic acid 5-methyl ester (4652-65-7) → α-p-Nitro-benzyl-γ-methyl-L-glutamat (96789-24-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / ethyl acetate / Heating

2: aq. HBr / acetic acid

With hydrogen bromide; triethylamine; In acetic acid; ethyl acetate;

DOI:10.1246/bcsj.37.200

Reference yield:

1-bromomethyl-4-nitro-benzene (100-11-8) → α-p-Nitro-benzyl-γ-methyl-L-glutamat (96789-24-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / ethyl acetate / Heating

2: aq. HBr / acetic acid

With hydrogen bromide; triethylamine; In acetic acid; ethyl acetate;

DOI:10.1246/bcsj.37.200

upstream raw materials:

N-Carbobenzoxy-<α-p-nitro-benzyl,γ-methyl>-L-glutamat

(S)-2-Benzyloxycarbonylamino-pentanedioic acid 5-methyl ester

1-bromomethyl-4-nitro-benzene

Downstream raw materials:

Carbobenzoxy-L-leucyl-<α-p-nitro-benzyl-γ-methyl>-L-glutamat

Carbobenzoxy-L-alanyl-<α-p-nitro-benzyl,γ-methyl>-L-glutamat

Carbobenzoxy-<γ-methyl>-L-glutamyl-<α-p-nitro-benzyl,γ-methyl>-L-glutamat

Z-Phe-<α-p-nitro-benzyl-γ-methyl>-Glu