1-(4-Methoxyphenyl)ethanone oxime

Base Information

• Chemical Name: 1-(4-Methoxyphenyl)ethanone oxime
• CAS No.: 2475-92-5
• Molecular Formula: C9H11 N O2
• Molecular Weight: 165.192
• European Community (EC) Number: 411-510-1
• NSC Number: 47502
• DSSTox Substance ID: DTXSID001020847
• Nikkaji Number: J579.856F,J899.237A
• Mol file: 2475-92-5.mol

Synonyms:1-(4-Methoxyphenyl)ethanone oxime;p-Methoxyacetophenone oxime;Acetophenone, 4'-methoxy-, oxime;Ethanone, 1-(4-methoxyphenyl)-, oxime;AI3-07283;(NZ)-N-[1-(4-methoxyphenyl)ethylidene]hydroxylamine;(E)-4'-Methoxyacetophenone oxime;DTXSID001020847;NSC47502;1-(p-Methoxyphenyl)acetaldehydeoxime;NSC 47502;NSC-47502;2-(4-methoxyphenyl)acetaldehyde oxime;AKOS004910202;LS-13633;EC 411-510-1;AN-308/25123014

Chemical Property of 1-(4-Methoxyphenyl)ethanone oxime

Chemical Property:

• Vapor Pressure: 0.00108mmHg at 25°C
• Boiling Point: 288.4°C at 760 mmHg
• Flash Point: 128.2°C
• Density: 1.06g/cm³
• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 165.078978594
• Heavy Atom Count: 12
• Complexity: 160

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NO)C1=CC=C(C=C1)OC
• Isomeric SMILES: C/C(=N/O)/C1=CC=C(C=C1)OC

Technology Process of 1-(4-Methoxyphenyl)ethanone oxime

There total 17 articles about 1-(4-Methoxyphenyl)ethanone oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-(4-methoxyphenyl)ethanone (100-06-1) → 4-methoxyacetophenone oxime (2475-92-5)

Guidance literature:

With hydroxylamine hydrochloride;

DOI:10.1021/jo902259u

Reference yield: 100.0%

1-(4-methoxyphenyl)ethanone (100-06-1) → (E)-1-(4-methoxyphenyl)ethanone oxime (2475-92-5)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In methanol; Heating;

DOI:10.1021/jo070297k

Reference yield: 93.0%

1-(4-methoxyphenyl)ethanamine (6298-96-0) → (E)-1-(4-methoxyphenyl)ethanone oxime (2475-92-5)

Guidance literature:

With Candida antarctica Lipase type B; urea hydrogen peroxide adduct; ethyl acetate; at 30 ℃; for 1h; under 760.051 Torr; Enzymatic reaction;

DOI:10.1039/c7ob00374a

upstream raw materials:

1-(4-Methoxyphenyl)-2-nitropropane

1-(4-methoxyphenyl)ethanone

4-methoxyphenylacetylen

1-(4-methoxyphenyl)ethanamine

Downstream raw materials:

N-(4-methoxyphenyl)thioacetamide

5-(4-chlorophenyl)-3-(4-methoxyphenyl)isoxazole

1-(4-Methoxy-phenyl)-ethanone O-(2-amino-ethyl)-oxime

N,N-dimethyl-N'-4-methoxy-phenylacetamidine

Refernces

• 1、 Liu, Yinghui,Wei, Yongjiao,Xie, Lan-Gui. "Dehydrative Beckmann rearrangement and the following cascade reactions". supporting information. . Retrieved 2021/11/16.
• 2、 Duarte, Marcelo,Jurberg, Igor D.,Le?o, Luiz Paulo M. O.,Saito, Felipe A.,Stivanin, Mateus L.. "Visible-Light-Mediated Strategies for the Preparation of Oxime Ethers Derived from O-H Insertions of Oximes into Aryldiazoacetates". supporting information. p. 17528 - 17532. Retrieved 2021/12/02.