benzyl N,N-bis(2-chloroethyl)-N'-(2,2,6,6-tetramethyl-4-piperidinyl)phosphorodiamidate

Base Information

• Chemical Name: benzyl N,N-bis(2-chloroethyl)-N'-(2,2,6,6-tetramethyl-4-piperidinyl)phosphorodiamidate
• CAS No.: 82576-67-8
• Molecular Formula: C₂₀H₃₄Cl₂N₃O₂P
• Molecular Weight: 450.389
• Mol file: 82576-67-8.mol

Synonyms:benzyl N,N-bis(2-chloroethyl)-N'-(2,2,6,6-tetramethyl-4-piperidinyl)phosphorodiamidate

Chemical Property of benzyl N,N-bis(2-chloroethyl)-N'-(2,2,6,6-tetramethyl-4-piperidinyl)phosphorodiamidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl N,N-bis(2-chloroethyl)-N'-(2,2,6,6-tetramethyl-4-piperidinyl)phosphorodiamidate

There total 2 articles about benzyl N,N-bis(2-chloroethyl)-N'-(2,2,6,6-tetramethyl-4-piperidinyl)phosphorodiamidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE (36768-62-4) + benzyl N,N-bis(2-chloroethyl)phosphoramidochloridate (82576-66-7) → benzyl N,N-bis(2-chloroethyl)-N'-(2,2,6,6-tetramethyl-4-piperidinyl)phosphorodiamidate (82576-67-8)

Guidance literature:

With sodium hydroxide; In benzene; at 0 ℃; for 4h;

DOI:10.1021/jm00351a021

Reference yield:

sodium phenyl-methanolate (20194-18-7) → benzyl N,N-bis(2-chloroethyl)-N'-(2,2,6,6-tetramethyl-4-piperidinyl)phosphorodiamidate (82576-67-8)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene / 2 h / 0 °C

2: 26 percent / 5N aq. NaOH / benzene / 4 h / 0 °C

With sodium hydroxide; In benzene;

DOI:10.1021/jm00351a021

Reference yield:

benzyl N,N-bis(2-chloroethyl)-N'-(2,2,6,6-tetramethyl-4-piperidinyl)phosphorodiamidate (82576-67-8) → benzyl N,N-bis(2-chloroethyl)-N'-(1-oxy-2,2,6,6-tetramethyl-4-piperidinyl)phosphorodiamidate (82576-68-9)

Guidance literature:

With sodium tungstate; dihydrogen peroxide; In ethanol; water; for 168h; Ambient temperature;

DOI:10.1021/jm00351a021

upstream raw materials:

4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE

benzyl N,N-bis(2-chloroethyl)phosphoramidochloridate

sodium phenyl-methanolate

Downstream raw materials:

benzyl N,N-bis(2-chloroethyl)-N'-(1-oxy-2,2,6,6-tetramethyl-4-piperidinyl)phosphorodiamidate

Refernces