CID 11979494

Base Information

• Chemical Name: CID 11979494
• CAS No.: 9000-55-9
• Molecular Formula: C88H92O34
• Molecular Weight: 1693.65168
• European Community (EC) Number: 232-546-2
• Wikipedia: Podophyllum_resin
• Wikidata: Q22075831
• Metabolomics Workbench ID: 152148
• Mol file: 9000-55-9.mol

Synonyms:Podophyllin;Podophyllum Resin;Resin, Podophyllum

Chemical Property of CID 11979494

Chemical Property:

• Appearance/Colour: light yellow to brown powder
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 433.18000
• Density: g/cm³
• LogP: 8.67700
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 34
• Rotatable Bond Count: 20
• Exact Mass: 1692.5470000
• Heavy Atom Count: 122
• Complexity: 1240

Purity/Quality:

99% ^*data from raw suppliers

Podophyllum resin ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T+
• Statements: 61-26/27/28-34
• Safety Statements: 53-26-27-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O.COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O.COC1=CC(=CC(=C1OC)OC)C2C(C(C(C3=CC4=C(C=C23)OCO4)O)CO)C(=O)O.COC1=CC(=CC(=C1OC)OC)C2C(C(C(C3=CC4=C(C=C23)OCO4)O)CO)C(=O)O
• Recent ClinicalTrials: Efficacy of Intralesional MMR Vaccine,Intralesional Candidal Antigen&Topical Podophyllin in Treatment of Genital Warts
• Uses: Common and plantar warts. Skin carcinomas, in various cancer treatments Podophyllin is a resin extracted from the root of the plant Podophyllum sp. Berberidaceae (mandrake), which contains numerous compounds, among which podophyllotoxin.
• Indications: Podophyllin in a 10% to 25% suspension in a tincture of benzoin or alcohol can be used with success. Since this compound contains two mutagens, quercetin and kaempherol, it should used with caution in the physician’s office. It should stay on for 1 to 4 hours and be applied every week for 4 to 6 weeks. Podofilox (0.05 mL of 5%) is safer than podophyllin and should be self-applied twice a day for 3 days followed by 4 rest days to complete a treatment cycle. Topical 0.5% podophyllotoxin cream has been used b.i.d. for 3 consecutive days for a maximum of 4 weeks with clearance in 54% of patients. Podophyllum resin (podophyllin), or podofilox, a cytotoxic agent that arrests mitosis in metaphase, is used primarily for treatment of condyloma acuminata but may also be used on all other types of warts. Although now rarely available, a 25% preparation of podophyllum in compound tincture of benzoin should be applied overnight when treating common nongenital warts. A more commonly available preparation, podofilox 0.5% gel (Condylox), should be applied twice a day for 3 days, then discontinued for 4 consecutive days. The same cycle is continued until eradication of the lesions. The effectiveness as well as the irritant potential of this medication may be increased by covering with adhesive tape or plastic tape (Blenderm).