6-(hept-6-en-1-yl)-2,4-dimethoxybenzoyl fluoride

Base Information

• Chemical Name: 6-(hept-6-en-1-yl)-2,4-dimethoxybenzoyl fluoride
• CAS No.: 1307285-90-0
• Molecular Formula: C₁₆H₂₁FO₃
• Molecular Weight: 280.339
• Mol file: 1307285-90-0.mol

Synonyms:6-(hept-6-en-1-yl)-2,4-dimethoxybenzoyl fluoride

Chemical Property of 6-(hept-6-en-1-yl)-2,4-dimethoxybenzoyl fluoride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-(hept-6-en-1-yl)-2,4-dimethoxybenzoyl fluoride

There total 4 articles about 6-(hept-6-en-1-yl)-2,4-dimethoxybenzoyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

6-(hept-6-en-1-yl)-2,4-dimethoxybenzoic acid (1307285-92-2) → 6-(hept-6-en-1-yl)-2,4-dimethoxybenzoyl fluoride (1307285-90-0)

Guidance literature:

With pyridine; trifluoro-[1,3,5]triazine; In dichloromethane; at 0 ℃; for 4h;

DOI:10.1055/s-0030-1258453

Reference yield:

6-(hept-6-en-1-yl)-2,4-dimethoxybenzaldehyde (1307285-91-1) → 6-(hept-6-en-1-yl)-2,4-dimethoxybenzoyl fluoride (1307285-90-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene; water / tert-butyl alcohol / 4 h

2: pyridine; trifluoro-[1,3,5]triazine / dichloromethane / 4 h / 0 °C

With pyridine; sodium chlorite; sodium dihydrogenphosphate; trifluoro-[1,3,5]triazine; 2-methyl-but-2-ene; water; In dichloromethane; tert-butyl alcohol; 1: Pinnick oxidation;

DOI:10.1055/s-0030-1258453

Reference yield:

1-iodo-3,5-dimethoxybenzene (25245-27-6) → 6-(hept-6-en-1-yl)-2,4-dimethoxybenzoyl fluoride (1307285-90-0)

Guidance literature:

Multi-step reaction with 4 steps

1: trichlorophosphate / 0 - 100 °C

2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; triphenyl-arsane; water; caesium carbonate / tetrahydrofuran; hexane; n-heptane; N,N-dimethyl-formamide / 16 h / 20 °C

3: sodium dihydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene; water / tert-butyl alcohol / 4 h

4: pyridine; trifluoro-[1,3,5]triazine / dichloromethane / 4 h / 0 °C

With pyridine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium chlorite; sodium dihydrogenphosphate; trifluoro-[1,3,5]triazine; 2-methyl-but-2-ene; triphenyl-arsane; water; caesium carbonate; trichlorophosphate; In tetrahydrofuran; hexane; n-heptane; dichloromethane; N,N-dimethyl-formamide; tert-butyl alcohol; 1: Vilsmeier-Haack reaction / 2: Suzuki coupling / 3: Pinnick oxidation;

DOI:10.1055/s-0030-1258453

upstream raw materials:

6-(hept-6-en-1-yl)-2,4-dimethoxybenzoic acid

6-(hept-6-en-1-yl)-2,4-dimethoxybenzaldehyde

1-iodo-3,5-dimethoxybenzene

2-iodo-4,6-dimethoxybenzaldehyde

Downstream raw materials:

(-)-(R)-but-3-en-2-yl 6-(hept-6-en-1-yl)-2,4-dimethoxybenzoate

Refernces