Avridine

Base Information

• Chemical Name: Avridine
• CAS No.: 35607-20-6
• Molecular Formula: C43H90 N2 O2
• Molecular Weight: 667.19
• Hs Code.: 2922199090
• UNII: P9J7O7YNSW
• DSSTox Substance ID: DTXSID70189078
• Nikkaji Number: J22.163E
• Wikidata: Q27286421
• NCI Thesaurus Code: C76685
• ChEMBL ID: CHEMBL2106042
• Mol file: 35607-20-6.mol

Synonyms:avridine;avridine phosphate (2:1);CP 20,961;CP 20961;CP-20,961;N,N-dioctyldecyl-N',N-bis(2-hydroxyethyl)propanediamine

Chemical Property of Avridine

Chemical Property:

• Vapor Pressure: 8.77E-24mmHg at 25°C
• Boiling Point: 717.6°Cat760mmHg
• Flash Point: 294.3°C
• PSA: 46.94000
• Density: 0.892g/cm³
• LogP: 12.48810
• Storage Temp.: Store at RT
• Solubility.: DMSO: ≥5mg/mL (with warming to 60 °C for 5 minutes)
• XLogP3: 17
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 42
• Exact Mass: 666.70023012
• Heavy Atom Count: 47
• Complexity: 504

Purity/Quality:

≥98% ^*data from raw suppliers

Avridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)CCCN(CCO)CCO
• Uses: A potent synthetic non-immunogenic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing.
• Therapeutic Function: Antiviral

Technology Process of Avridine

There total 2 articles about Avridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methylene chloride-water + methylene chloride (9.75 liters)-water + 2,2'-[(3-aminopropyl)imino]bis-ethanol (4985-85-7) + silicic acid (7699-41-4) + 1-Bromooctadecane (112-89-0) → N,N-dioctadecyl-N',N'-bis(2-hydroxyethyl)1,3-propanediamine (35607-20-6)

Guidance literature:

With sodium hydroxide; succinic acid; potassium carbonate; In dichloromethane; acetone;

Reference yield:

→ N,N-dioctadecyl-N',N'-bis(2-hydroxyethyl)1,3-propanediamine (35607-20-6)

Guidance literature:

Diamin, Alkyl.;

upstream raw materials:

2,2'-[(3-aminopropyl)imino]bis-ethanol

silicic acid

1-Bromooctadecane

Refernces

• 1、 -. "Synthetic immunogen". . . Retrieved 2008/06/13.