Triethylene glycol monooctadecyl ether

Base Information

• Chemical Name: Triethylene glycol monooctadecyl ether
• CAS No.: 9005-00-9
• Molecular Formula: C₂₄H₅₀O₄
• Molecular Weight: 402.659
• Hs Code.: 39072020
• European Community (EC) Number: 610-180-8
• UNII: 148NZZ5LUI
• DSSTox Substance ID: DTXSID60891638
• Nikkaji Number: J2.819.373D
• Wikidata: Q27251606
• Mol file: 9005-00-9.mol

Synonyms:4439-32-1;Triethylene glycol monooctadecyl ether;C18E3;STEARETH-3;2-[2-(2-octadecoxyethoxy)ethoxy]ethanol;Trioxyethylene stearyl ether;PEG-3 stearyl ether;2-(2-(2-(Octadecyloxy) ethoxy)ethoxy)ethanol;2-{2-[2-(octadecyloxy)ethoxy]ethoxy}ethan-1-ol;UNII-148NZZ5LUI;148NZZ5LUI;2-(2-(2-(octadecyloxy)ethoxy)ethoxy)ethanol;3,6,9-Trioxaheptacosan-1-ol;2-[2-[2-(Octadecyloxy)ethoxy]ethoxy]ethanol;C18EOx;3,6,9-trioxaheptacosanol;STEARETH-3 [INCI];SCHEMBL1725212;DTXSID60891638;MFCD00043358;AKOS025395291;AS-3199;TRIETHYLENE GLYCOL STEARYL ETHER;FT-0742042;A918631;Ethanol, 2-(2-(2-(octadecyloxy)ethoxy)ethoxy)-;Q27251606

Chemical Property of Triethylene glycol monooctadecyl ether

Chemical Property:

• Appearance/Colour: solid
• Vapor Pressure: 0Pa at 20℃
• Melting Point: 56-60oC
• Boiling Point: 100oC
• Flash Point: 154.2oC
• PSA: 0.00000
• Density: 0.867g/cm3
• LogP: 0.00000
• Solubility.: propylene glycol and xylene: insoluble
• Water Solubility.: 50ng/L at 20℃
• XLogP3: 8.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 25
• Exact Mass: 402.37091007
• Heavy Atom Count: 28
• Complexity: 261

Purity/Quality:

99.9% ^*data from raw suppliers

Polyoxyl 20 cetostearyl ether United States Pharmacopeia (USP) Reference Standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 36-22-41
• Safety Statements: 26-36-39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCCOCCOCCOCCO

Technology Process of Triethylene glycol monooctadecyl ether

There total 31 articles about Triethylene glycol monooctadecyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl octadecyloxyacetate (6064-94-4) → 3-oxa-1-heneicosanol (2136-72-3,9005-00-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 3h; Heating;

Reference yield: 83.0%

1-octadecyl methanesulfonate (31081-59-1) + ethylene glycol (107-21-1) → 3-oxa-1-heneicosanol (2136-72-3,9005-00-9)

Guidance literature:

With potassium tert-butylate; at 80 ℃; for 5h;

Reference yield: 56.0%

1-Bromooctadecane (112-89-0) → 2-(2-n-octadecyloxyethoxy)ethanol (16057-43-5,9005-00-9)

Guidance literature:

In water; N,N-dimethyl-formamide; diethylene glycol;

upstream raw materials:

n-octadecyl p-toluenesulfonate

ethylene glycol

methyl octadecyloxyacetate

Acetic acid 2-octadecyloxy-ethyl ester

Downstream raw materials:

2-(octadecyloxy)ethyl dihydrogen phosphate

Refernces

• 1、 -. "Lipid modified spermine derivatives and the use of the derivatives of the prepared liposome". Paragraph 0200-0202; 0205-0206. . Retrieved 2017/08/25.
• 2、 Singh, Rajkumar Sunil,Mukherjee, Koushik,Banerjee, Rajkumar,Chaudhuri, Arabinda,Hait, Samik Kumar,Moulik, Satya Priya,Ramadas, Yerramsetti,Vijayalakshmi, Amash,Rao, Nalam Madhusudhana. "Anchor dependency for non-glycerol based cationic lipofectins: Mixed bag of regular and anomalous transfection profiles". . p. 900 - 909. Retrieved 2007/10/03.