Technology Process of 1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone
There total 30 articles about 1-(3,5-Dichloro-4-fluorophenyl)-2,2,2-trifluoroethanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
magnesium;
In
tetrahydrofuran; ethylene dibromide;
at 20 ℃;
for 6h;
In
tetrahydrofuran; ethylene dibromide;
at 20 ℃;
for 1.33333h;
- Guidance literature:
-
5-bromo-1,3-dichloro-2-fluorobenzene;
With
magnesium;
In
tetrahydrofuran; ethylene dibromide;
at 20 ℃;
for 6h;
N,N-diethyl-2,2,2-trifluoroacetamide;
In
tetrahydrofuran; ethylene dibromide;
at 20 ℃;
for 1.33333h;
- Guidance literature:
-
2-fluoro-3-chloro-5-trifluoroacetylaniline;
With
nitrosylsulfuric acid; sulfuric acid;
at 45 ℃;
for 1h;
With
hydrogenchloride; copper(l) chloride;
In
water;
at 40 - 50 ℃;
for 2h;
Temperature;