N-(2-bromophenyl)cyanamide

Base Information

• Chemical Name: N-(2-bromophenyl)cyanamide
• CAS No.: 343269-59-0
• Molecular Formula: C₇H₅BrN₂
• Molecular Weight: 197.034
• Mol file: 343269-59-0.mol

Synonyms:N-(2-bromophenyl)cyanamide

Chemical Property of N-(2-bromophenyl)cyanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(2-bromophenyl)cyanamide

There total 9 articles about N-(2-bromophenyl)cyanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-(2-bromophenyl)thiourea (5391-30-0) → N-(2-bromophenyl)cyanamide (343269-59-0)

Guidance literature:

With copper(l) iodide; sodium hydroxide; In N,N-dimethyl-formamide; at 90 ℃; for 2h;

DOI:10.1002/adsc.201000383

Reference yield: 91.0%

1-phenylcyanamide (622-34-4) → N-(2-bromophenyl)cyanamide (343269-59-0)

Guidance literature:

With N-Bromosuccinimide; 2,6-di-tert-butyl-4-methyl-phenol; palladium diacetate; In 1,2-dichloro-ethane; at 80 ℃; for 8h; Reagent/catalyst; Solvent; Temperature; regioselective reaction; Catalytic behavior; Mechanism; Green chemistry;

DOI:10.1039/d1nj01998h

Reference yield: 85.0%

C7H5(2)HN2 → N-(2-bromophenyl)cyanamide (343269-59-0) + C7H4(2)HBrN2

Guidance literature:

With N-Bromosuccinimide; 2,6-di-tert-butyl-4-methyl-phenol; palladium diacetate; In 1,2-dichloro-ethane; at 80 ℃; for 8h; regioselective reaction; Kinetics; Mechanism; Green chemistry;

DOI:10.1039/d1nj01998h

upstream raw materials:

bromocyane

2-bromoaniline

1-(2-bromophenyl)thiourea

2-bromobenzamidoxime

Downstream raw materials:

N'-(2-bromo phenyl)-urea

2-[(2-bromophenyl)amino]benzonitrile

Refernces

• 1、 Ding, Chengrong,Ge, Shuting,Wei, Junjie,Zhang, Guofu,Zhao, Yiyong. "SO2F2-Mediated one-pot cascade process for transformation of aldehydes (RCHO) to cyanamides (RNHCN)". . p. 17288 - 17292. Retrieved 2020/05/18.
• 2、 Rao, Bin,Zeng, Xiaoming. "Aminocyanation by the addition of N-CN bonds to arynes: Chemoselective synthesis of 1,2-bifunctional aminobenzonitriles". supporting information. p. 314 - 317. Retrieved 2014/01/23.