Cyclohexyltriphenylphosphonium bromide

Base Information

• Chemical Name: Cyclohexyltriphenylphosphonium bromide
• CAS No.: 7333-51-9
• Molecular Formula: C24H26BrP
• Molecular Weight: 425.348
• Hs Code.: 29310099
• European Community (EC) Number: 230-834-2
• DSSTox Substance ID: DTXSID40994055
• Mol file: 7333-51-9.mol

Synonyms:Cyclohexyltriphenylphosphonium bromide;7333-51-9;EINECS 230-834-2;cyclohexyl triphenylphosphonium bromide;cyclohexyl(triphenyl)phosphanium;bromide;cyclohexyl(triphenyl)phosphanium bromide;C24H26P.Br;SCHEMBL2445980;C24-H26-P.Br;DTXSID40994055;QRAKRDZMIONMRZ-UHFFFAOYSA-M;Cyclohexyltriphenylphosphoniumbromide;Cyclohexyltriphenylphosphomium bromide;MFCD00031667;AKOS015833062;CS-0455382;FT-0624208;A837792

Chemical Property of Cyclohexyltriphenylphosphonium bromide

Chemical Property:

• Appearance/Colour: white to beige crystalline powder
• Melting Point: 265-272 °C
• PSA: 13.59000
• LogP: 2.31720
• Sensitive.: Hygroscopic
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 424.09555
• Heavy Atom Count: 26
• Complexity: 333

Purity/Quality:

98%,99%, ^*data from raw suppliers

CyclohexyltriphenylphosphoniumBromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Br-]
• Uses: Bromo(cyclohexyl)triphenylphosphorane was used as a reactant for Wittig reactions.

Technology Process of Cyclohexyltriphenylphosphonium bromide

There total 3 articles about Cyclohexyltriphenylphosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromocyclohexane (108-85-0) + triphenylphosphine (603-35-0) → cyclohexyl(triphenyl)phosphonium bromide (7333-51-9)

Guidance literature:

In benzene; Heating;

DOI:10.1039/a703033i

Reference yield:

1,5-dibromo-pentane (111-24-0) + Methylenetriphenylphosphorane (19493-09-5) → cyclohexyl(triphenyl)phosphonium bromide (7333-51-9)

Guidance literature:

Reference yield:

→ cyclohexyl(triphenyl)phosphonium bromide (7333-51-9)

Guidance literature:

DOI:10.1016/0009-3084(71)90053-3 DOI:10.1021/jo01271a094

upstream raw materials:

1,5-dibromo-pentane

Methylenetriphenylphosphorane

1-bromocyclohexane

triphenylphosphine

Downstream raw materials:

1,1-difluoromethylenecyclohexane

2-(cyclohexylidenemethyl)pyridine

1,1-diphenylmethylenecyclohexane

((1-(cyclohexylidenemethyl)cyclopropyl)ethynyl)benzene

Refernces

• 1、 -. "P2Y12 receptor antagonists diphenyl thioacetic acid, preparation method and use thereof (by machine translation)". Paragraph 0022-0025. . Retrieved 2018/07/06.
• 2、 Duan, Xiao-Guang,Duan, Xiao-Lan,Rees, Charles W.. "Reaction of trithiazyl trichloride with active methylene compounds". . p. 2831 - 2836. Retrieved 2007/10/03.