2-Bromopropanal

Base Information

• Chemical Name: 2-Bromopropanal
• CAS No.: 19967-57-8
• Molecular Formula: C3H5 Br O
• Molecular Weight: 136.976
• Hs Code.: 2913000090
• European Community (EC) Number: 822-714-9
• NSC Number: 513362
• DSSTox Substance ID: DTXSID40325623
• Nikkaji Number: J665.957H
• Mol file: 19967-57-8.mol

Synonyms:2-bromopropanal;19967-57-8;Propanal, 2-bromo-;2-bromo-propionaldehyde;Propanal, 2-bromo- (9CI);2-bromopropionaldehyde;NSC513362;a-bromopropionaldehyde;SCHEMBL300957;DTXSID40325623;AKOS006238811;NSC 513362;NSC-513362;FT-0696894;EN300-60203;A814118

Chemical Property of 2-Bromopropanal

Chemical Property:

• Vapor Pressure: 26.2mmHg at 25°C
• Melting Point: 48-55 °C
• Refractive Index: 1.4813
• Boiling Point: 108.2°Cat760mmHg
• Flash Point: 61.3°C
• PSA: 17.07000
• Density: 1.54g/cm³
• LogP: 0.96870
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 135.95238
• Heavy Atom Count: 5
• Complexity: 35.9

Purity/Quality:

99%, ^*data from raw suppliers

2-bromopropanal ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C=O)Br

Technology Process of 2-Bromopropanal

There total 16 articles about 2-Bromopropanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

propionaldehyde (123-38-6) → bromo-2 propanal (19967-57-8)

Guidance literature:

With bromine; In dichloromethane; for 0.5h; Inert atmosphere;

DOI:10.5012/bkcs.2013.34.1.271

Reference yield: 87.0%

2-methyl-3-nitro-oxirane (39583-27-2) → bromo-2 propanal (19967-57-8)

Guidance literature:

With magnesium bromide; In diethyl ether; at -10 ℃; for 0.5h;

Reference yield: 37.0%

2-bromo-1,1-dimethoxypropane (33170-72-8) → bromo-2 propanal (19967-57-8)

Guidance literature:

With trifluoroacetic acid; In chloroform; at 20 ℃; for 4h;

upstream raw materials:

dimethoxypropane

1-(1,2-dibromopropyl)-4-methoxybenzene

4-(1,2-dibromo-propyl)-1,2-dimethoxy-benzene

propionaldehyde

Downstream raw materials:

hydroxy-2-propanone

5-methylthiazole

2-benzyl-5-methyl-thiazole

benzaldehyde (5-methyl-selenazol-2-yl)-hydrazone

Refernces

• 1、 -. "PYRROLO[1,2-A]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS". Paragraph 00326. . Retrieved 2017/11/04.
• 2、 Nam, Kee Dal,Han, Minsoo,Yoon, Jun,Kim, Eun-A,Cho, Sung-Woo,Hahn, Hoh-Gyu. "2-amino-1,3-thiazoles suppressed lipopolysaccharide-induced il-β and TNF-α". . p. 271 - 274. Retrieved 2013/08/24.