Technology Process of Pericine
There total 34 articles about Pericine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-[(E)-2-ethylidene-11b-(hydroxymethyl)-2,3,5,6,11,11b-hexahydro-1H-indolizino(8,7-b)indol-1-yl]ethan-1-ol;
With
dmap; triethylamine; p-toluenesulfonyl chloride;
In
tetrahydrofuran;
at 0 - 25 ℃;
for 6h;
With
lithium bromide;
In
tetrahydrofuran;
for 3h;
Reflux;
With
zinc;
In
tetrahydrofuran;
for 3h;
Reflux;
DOI:10.1021/acs.joc.7b02122
- Guidance literature:
-
(+)-2-[(1S,11bS,E)-2-ethylidene-11b-(hydroxymethyl)-2,3,5,6,11,11b-hexahydro-1H-indolizino(8,7-b)indol-1-yl]ethan-1-ol;
With
dmap; triethylamine; p-toluenesulfonyl chloride;
In
tetrahydrofuran;
at 0 - 25 ℃;
for 6h;
With
lithium bromide;
In
tetrahydrofuran;
for 3h;
Reflux;
With
zinc;
In
tetrahydrofuran;
for 3h;
Reflux;
DOI:10.1021/acs.joc.7b02122
