4-Chloroformylphthalic anhydride

Base Information

• Chemical Name: 4-Chloroformylphthalic anhydride
• CAS No.: 1204-28-0
• Molecular Formula: C9H3ClO4
• Molecular Weight: 210.573
• Hs Code.: 29173990
• European Community (EC) Number: 214-874-8
• NSC Number: 89728
• UNII: 56231EU26X
• DSSTox Substance ID: DTXSID9061621
• Nikkaji Number: J60.340F
• Wikipedia: Trimellitic_anhydride_chloride
• Wikidata: Q7842162
• Mol file: 1204-28-0.mol

Synonyms:Phthalicanhydride, 4-(chloroformyl)- (7CI,8CI);1,3-Benzofurandione-5-carbonylchloride;1,3-Dioxo-1,3-dihydro-2-benzofuran-5-carbonyl chloride;4-(Chlorocarbonyl)phthalic anhydride;4-(Chloroformyl)phthalic anhydride;Anhydrotrimellitic acid chloride;NSC 89728;Trimellitic acid anhydride4-monoacid chloride;Trimellitic acid anhydride chloride;Trimellitic anhydrideacid chloride;Trimellitic anhydride chloride;Trimellitic anhydride monoacidchloride;Trimellitic anhydride monochloride;

Chemical Property of 4-Chloroformylphthalic anhydride

Chemical Property:

• Appearance/Colour: white crystalline solid
• Vapor Pressure: 0.017Pa at 20℃
• Melting Point: 66-69 ºC
• Refractive Index: 1.4571 (estimate)
• Boiling Point: 391.4°Cat760mmHg
• Flash Point: 186.3°C
• PSA: 60.44000
• Density: 1.632g/cm³
• LogP: 1.37620
• Storage Temp.: 2-8°C
• Sensitive.: Moisture Sensitive
• Water Solubility.: decomposes
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 209.9719863
• Heavy Atom Count: 14
• Complexity: 312

Purity/Quality:

Trimellitic anhydride chloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34-29
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC2=C(C=C1C(=O)Cl)C(=O)OC2=O

Technology Process of 4-Chloroformylphthalic anhydride

There total 2 articles about 4-Chloroformylphthalic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.9%

trimellitic Anhydride (552-30-7,145253-53-8) → trimellitic anhydride acid chloride (1204-28-0)

Guidance literature:

With dmap; thionyl chloride; In cyclohexane; at 90 ℃; for 6h; Solvent; Temperature; Reagent/catalyst;

Reference yield:

→ trimellitic anhydride acid chloride (1204-28-0)

Guidance literature:

DOI:10.1007/BF00863204 DOI:10.1021/jo00954a034

Reference yield: 99.0%

trimellitic anhydride acid chloride (1204-28-0) → phthalic anhydride (85-44-9) + 4-chlorophthalic anhydride (118-45-6)

Guidance literature:

palladium dichloride; In melt; at 290 ℃; for 2h; Product distribution; other temperatures and other catalysts (Pd/C, Pd(PPh₃)4);

DOI:10.1016/S0040-4039(00)86833-1

upstream raw materials:

trimellitic Anhydride

Downstream raw materials:

4-(5-phenyloxazol-2-yl)phthalic anhydride

benzene-1,2,4-tricarboxylic acid 4<(6R-trans)-(2-benzhydryloxycarbonyl-8-oxo-7-phenylacetylamino-5-thia-1-azabicyclo<4.2.0>oct-2-en-3-yl)methyl> ester

benzene-1,2,4-tricarboxylic acid 4<(6R-trans)-(2-benzhydryloxycarbonyl-5,8-dioxo-7-phenylacetylamino-5-thia-1-azabicyclo<4.2.0>oct-2-en-3-yl)methyl> ester

4-(Trimethylsilyl)phthalic anhydride

Refernces

• 1、 Li, Zi-Hao,Fiser, Béla,Jiang, Biao-Lin,Li, Jian-Wei,Xu, Bao-Hua,Zhang, Suo-Jiang. "N -Hydroxyphthalimide/benzoquinone-catalyzed chlorination of hydrocarbon C-H bond using N -chlorosuccinimide". supporting information. p. 3403 - 3408. Retrieved 2019/04/01.
• 2、 -. "Modular RNA regulators and methods". Page/Page column 2-3. . Retrieved 2018/10/30.