BETA-D-GAL-[1->3]-D-GALNAC

Base Information

• Chemical Name: BETA-D-GAL-[1->3]-D-GALNAC
• CAS No.: 3554-90-3
• Molecular Formula: C14H25 N O11
• Molecular Weight: 383.353
• Mol file: 3554-90-3.mol

Synonyms:Galactose,2-acetamido-2-deoxy-3-O-b-D-galactopyranosyl-, D- (7CI,8CI); D-Galactosyl-b1®3-D-N-acetylglucosamine; O-b-D-Galactopyranosyl-(1®3)-N-acetylgalactosamine; b-D-Galactosyl-(1-3)-N-acetylgalactosamine; b-D-Galactosyl-(1®3)-N-acetyl-D-galactosamine; b-Galactosyl-(1®3)-N-acetylgalactosamine

Chemical Property of BETA-D-GAL-[1->3]-D-GALNAC

Chemical Property:

• Vapor Pressure: 2.63E-34mmHg at 25°C
• Melting Point: 159-160°C
• Boiling Point: 858.1°C at 760 mmHg
• Flash Point: 472.8°C
• PSA: 206.24000
• Density: 1.58g/cm³
• LogP: -5.01990
• Storage Temp.: −20°C
• Solubility.: Methanol (Slightly, Heated), Water (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

2-Acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-D-galactose ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: It is found in hydrolysates of blood group A,B,H, and Le substances and forms an essential part of their antigenic determinants. It is also inherent in the structure of the brain gangliosides in which it constitutes the terminal part of the molecule. It is found in hydrolysates of blood group A,B,H, and the substances and forms an essential part of their antigenic determinants. It is also inherent in the structure of the brain gangliosides in which it constitutes the terminal part of the molecule.

Technology Process of BETA-D-GAL-[1->3]-D-GALNAC

There total 3 articles about BETA-D-GAL-[1->3]-D-GALNAC which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

uridine 5'-diphospho-D-galactose (2956-16-3) + 4-methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside (124223-99-0) → β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-D-galactose (3554-90-3,60283-31-0) + 7-hydroxy-4-methyl-chromen-2-one (90-33-5,79566-13-5) + UDP (58-98-0)

Guidance literature:

With endo-α-N-acetylgalactosaminidase; manganese(ll) chloride; at 37 ℃; for 1h; pH=6.8; aq. buffer; Enzymatic reaction;

DOI:10.1093/glycob/cwq168

Reference yield:

N-acetylgalactosamine (134-61-2,3615-17-6,4773-29-9,6813-82-7,7436-28-4,7512-17-6,20770-61-0,20880-43-7,20880-45-9,23583-38-2,23655-50-7,31022-50-1,50985-77-8,134451-94-8,149054-75-1,1811-31-0,282727-46-2,478518-83-1,127959-06-2,78393-48-3) + D-galactopyranose 1-phosphate (27251-84-9,63779-58-8,262856-84-8) → β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-D-galactose (3554-90-3,60283-31-0)

Guidance literature:

With D-galactosyl-β1–3-N-acetyl-D-hexosamine phosphorylase; Enzymatic reaction;

DOI:10.1021/jacs.6b07132

Reference yield:

D-Mannose (3458-28-4) + N-acetylgalactosamine (134-61-2,3615-17-6,4773-29-9,6813-82-7,7436-28-4,7512-17-6,20770-61-0,20880-43-7,20880-45-9,23583-38-2,23655-50-7,31022-50-1,50985-77-8,134451-94-8,149054-75-1,1811-31-0,282727-46-2,478518-83-1,127959-06-2,78393-48-3) → β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-D-galactose (3554-90-3,60283-31-0) + N-[(1R,2R,3R,4R)-1-Formyl-2,3,4-trihydroxy-5-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-pentyl]-acetamide (72142-81-5) + 2-acetylamino-O4-β-D-galactopyranosyl-2-deoxy-D-galactose (82535-18-0,50787-11-6,82441-98-3,85441-65-2)

Guidance literature:

With phosphate buffer; β-galactosidase; In N,N-dimethyl-formamide; at 37 ℃; pH=6.0; Further Variations:; Reagents; Product distribution;

DOI:10.1271/bbb.68.2086

upstream raw materials:

D-Mannose

N-acetylgalactosamine

uridine 5'-diphospho-D-galactose

4-methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside

Downstream raw materials:

sialyl-T antigen

D-Galactose

2-acetamido-3,6-anhydro-2-deoxy-α-D-idofuranose

2-acetamido-3,6-anhydro-2-deoxy-α-D-gulofuranose

Refernces

• 1、 Ju, Tongzhong,Xia, Baoyun,PAryal, Rajindra,Wang, Wenyi,Wang, Yingchun,Ding, Xiaokun,Mi, Rongjuan,He, Miao,Richard D. Cummings. "A novel fluorescent assay for T-synthase activity". experimental part. p. 352 - 362. Retrieved 2011/10/09.