2',4',6',3-Tetrahydroxy-4-methoxychalcone

Base Information

• Chemical Name: 2',4',6',3-Tetrahydroxy-4-methoxychalcone
• CAS No.: 75679-30-0
• Molecular Formula: C16H14O6
• Molecular Weight: 302.284
• DSSTox Substance ID: DTXSID10432651
• Nikkaji Number: J617.702F
• Wikidata: Q82246741
• Mol file: 75679-30-0.mol

Synonyms:Hesperetin chalcone;75679-30-0;2',4',6',3-Tetrahydroxy-4-methoxychalcone;(E)-3-(3-hydroxy-4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one;DTXSID10432651

Chemical Property of 2',4',6',3-Tetrahydroxy-4-methoxychalcone

Chemical Property:

• PSA: 107.22000
• LogP: 2.41370
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 302.07903816
• Heavy Atom Count: 22
• Complexity: 397

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)C=CC(=O)C2=C(C=C(C=C2O)O)O)O
• Isomeric SMILES: COC1=C(C=C(C=C1)/C=C/C(=O)C2=C(C=C(C=C2O)O)O)O

Technology Process of 2',4',6',3-Tetrahydroxy-4-methoxychalcone

There total 3 articles about 2',4',6',3-Tetrahydroxy-4-methoxychalcone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hesperidin (520-26-3) → Hesperetin chalcone (75679-30-0)

Guidance literature:

With sulfuric acid; acetic anhydride; erhitzen mit wss.Aethanol und Schwefelsaeure;

Reference yield:

2,4,6-trihydroxyacetophenone (480-66-0,67471-34-5) + vanillin (121-33-5,8014-42-4) → Hesperetin chalcone (75679-30-0)

Guidance literature:

With hydrogenchloride;

Reference yield:

→ Hesperetin chalcone (75679-30-0)

Guidance literature:

1-<2,4,6-Trihydroxy-phenyl>-aethanon, entspr. Benzaldehyd;

upstream raw materials:

2,4,6-trihydroxyacetophenone

vanillin

hesperidin

Downstream raw materials:

hesperetin