fluorescein dianion

Base Information

• Chemical Name: fluorescein dianion
• CAS No.: 53677-98-8
• Molecular Formula: C₂₀H₁₀O₅
• Molecular Weight: 330.296
• Mol file: 53677-98-8.mol

Synonyms:fluorescein dianion

Chemical Property of fluorescein dianion

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of fluorescein dianion

There total 7 articles about fluorescein dianion which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

fluorescein diacetate (596-09-8) → fluorescein dianion (53677-98-8)

Guidance literature:

With carboxyesterase; N,N-diethy-N-(4-(1,2,2-triphenylvinyl)benzyl)lhexadecan-1-aminium; In dimethyl sulfoxide; at 37 ℃; for 0.5h; pH=7.4; Enzymatic reaction;

DOI:10.1039/c5cc04771d

Reference yield:

fluorescein (2321-07-5,126605-73-0) → fluorescein dianion (53677-98-8)

Guidance literature:

Multi-step reaction with 2 steps

1: Reflux

2: N,N-diethy-N-(4-(1,2,2-triphenylvinyl)benzyl)lhexadecan-1-aminium; carboxyesterase / dimethyl sulfoxide / 0.5 h / 37 °C / pH 7.4 / Enzymatic reaction

With carboxyesterase; N,N-diethy-N-(4-(1,2,2-triphenylvinyl)benzyl)lhexadecan-1-aminium; In dimethyl sulfoxide;

DOI:10.1039/c5cc04771d

Reference yield:

2-amino-3′,6′-dihydroxyspiro[isoindoline-1,9′-xanthen]-3-one (98907-26-7) → fluorescein dianion (53677-98-8)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 78 °C

2: sodium hypochlorite / water

With sodium hypochlorite; In ethanol; water;

DOI:10.1016/j.tet.2016.02.004

upstream raw materials:

fluorescein

fluorescein diacetate

2-amino-3′,6′-dihydroxyspiro[isoindoline-1,9′-xanthen]-3-one

Downstream raw materials:

leuco-fluorescein

Refernces

• 1、 Asthana, Sharad Kumar,Kumar, Ajit,Neeraj,Upadhyay. "A reaction based chromofluorogenic turn-on probe for specific detection of fluoride over sulfide/thiols". . p. 5988 - 5992. Retrieved 2014.
• 2、 Algi, Melek Pamuk. "A highly selective dual channel hypochlorite probe based on fluorescein and 1,10-phenanthroline". . p. 1558 - 1565. Retrieved 2016/03/01.