1,3-bis-biphenyl-4-ylpropenone

Base Information

• Chemical Name: 1,3-bis-biphenyl-4-ylpropenone
• CAS No.: 23274-53-5
• Molecular Formula: C₂₇H₂₀O
• Molecular Weight: 360.455
• Mol file: 23274-53-5.mol

Synonyms:1,3-bis-biphenyl-4-ylpropenone

Chemical Property of 1,3-bis-biphenyl-4-ylpropenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-bis-biphenyl-4-ylpropenone

There total 7 articles about 1,3-bis-biphenyl-4-ylpropenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(E)-1,3-bis(4-bromophenyl)prop-2-en-1-one (5471-96-5,126443-21-8) + phenylboronic acid (98-80-6) → (E)-1,3-di([1,1'-biphenyl]-4-yl)prop-2-en-1-one (23274-53-5)

Guidance literature:

With sodium carbonate; In 1,2-dimethoxyethane; water;

DOI:10.2174/157017809789869564

Reference yield: 76.0%

para-bromoacetophenone (99-90-1) + 4-bromo-benzaldehyde (1122-91-4) + phenylboronic acid (98-80-6) → (E)-1,3-di([1,1'-biphenyl]-4-yl)prop-2-en-1-one (23274-53-5)

Guidance literature:

With tetrabutylammomium bromide; palladium diacetate; potassium carbonate; In water; at 90 ℃; for 4h; Green chemistry;

DOI:10.1002/chem.201303069

Reference yield: 26.0%

biphenyl-4-acetaldehyde (92-91-1) + 4-Phenylbenzaldehyde (3218-36-8) → (E)-1,3-di([1,1'-biphenyl]-4-yl)prop-2-en-1-one (23274-53-5)

Guidance literature:

With sodium hydroxide; In ethanol; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.8b02945

upstream raw materials:

biphenyl-4-acetaldehyde

4-Phenylbenzaldehyde

(E)-1,3-Bis-biphenyl-4-yl-prop-2-en-1-ol

(E)-1,3-bis(4-bromophenyl)prop-2-en-1-one

Downstream raw materials:

(E)-1,3-bis(4-biphenylyl)-prop-2-en-1-ol

(E)-1,3-Bis-biphenyl-4-yl-prop-2-en-1-ol

3,5-di(biphenyl-4-yl)-1-phenyl-4,5-dihydro-1H-pyrazole

Refernces

• 1、 Chan, Chieh-Kai,Tsai, Yu-Lin,Chang, Meng-Yang. "Bi(OTf)3 catalyzed disproportionation reaction of cinnamyl alcohols". . p. 3368 - 3376. Retrieved 2017/05/22.
• 2、 Patel, Heta A.,Patel, Arun L.,Bedekar, Ashutosh V.. "Polyaniline coated on celite, a heterogeneous support for palladium: Applications in catalytic Suzuki and one-pot Suzuki-aldol reactions". . p. 8935 - 8945. Retrieved 2016/10/13.