CS 542 and 543

Base Information

• Chemical Name: CS 542 and 543
• CAS No.: 64952-14-3
• Molecular Formula: C₆H₁₀O₅
• Molecular Weight: 162.142
• NSC Number: 68105
• DSSTox Substance ID: DTXSID00418186
• Wikidata: Q82228562
• Mol file: 64952-14-3.mol

Synonyms:WY 2380;64952-14-3;CS 542 and 543;Propanal, [R-(R*,R*)]-;DTXSID00418186;NSC68105;NSC-68105;Diglycolaldehyde, D-.alpha.-(hydroxymethyl)-D-.alpha.'-methoxy-

Chemical Property of CS 542 and 543

Chemical Property:

• Vapor Pressure: 0.0119mmHg at 25°C
• Boiling Point: 231.3°C at 760 mmHg
• Flash Point: 90.7°C
• Density: 1.217g/cm³
• XLogP3: -1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 162.05282342
• Heavy Atom Count: 11
• Complexity: 124

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(C=O)OC(CO)C=O
• Isomeric SMILES: CO[C@@H](C=O)O[C@H](CO)C=O

Technology Process of CS 542 and 543

There total 5 articles about CS 542 and 543 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

methyl beta-D-glucopyranoside (709-50-2) → (R)-3-hydroxy-2-((R)-1-methoxy-2-oxo-ethoxy)-propionaldehyde (64952-14-3)

Guidance literature:

With sodium periodate; In water; at 10 ℃; for 0.666667h;

DOI:10.1016/j.carres.2009.03.016

Reference yield:

methyl beta-D-galactopyranoside (1824-94-8) → (R)-3-hydroxy-2-((R)-1-methoxy-2-oxo-ethoxy)-propionaldehyde (64952-14-3)

Guidance literature:

With water; periodic acid; at 20 ℃;

Reference yield:

Methyl mannoside (22277-65-2) → (R)-3-hydroxy-2-((R)-1-methoxy-2-oxo-ethoxy)-propionaldehyde (64952-14-3)

Guidance literature:

With water; periodic acid; at 20 ℃;

upstream raw materials:

Methyl mannoside

methyl beta-D-glucopyranoside

methyl beta-D-galactopyranoside

1-O-methyl-D-ribofuranose

Downstream raw materials:

3-Nitro-3-deoxy-β-D-mannopyranose-methylglucosid

methyl 3-nitro-β-D-3-deoxy-glucopyranoside

3-Nitro-3-deoxy-β-D-galactopyranose-methylglucosid

2-[(R)-1-methoxy-2-(4-nitro-benzoyloxy)-ethoxy]-1,3-bis-(4-nitro-benzoyloxy)-propane

Refernces

• 1、 Simak, Ondrej,Stanek, Jan,Moravcova, Jitka. "A stereocontrolled synthesis of 3-acetamido-1,3,5-trideoxy- and 1,3,5,6-tetradeoxy-1,5-imino-d-glucitol". experimental part. p. 966 - 971. Retrieved 2009/09/05.
• 2、 Kolar, Cenek,Kneissl, Guenther,Knoedler, Ursula,Dehmel, Konrad. "Semisynthetic ε-(iso)rhodomycins: a new glycosylation variant and modification reactions". . p. 89 - 100. Retrieved 2007/10/02.