3,4-Dichloro-2(5H)-furanone

Base Information

• Chemical Name: 3,4-Dichloro-2(5H)-furanone
• CAS No.: 62674-12-8
• Molecular Formula: C4H2Cl2O2
• Molecular Weight: 152.965
• Hs Code.: 2932209090
• European Community (EC) Number: 686-997-9
• NSC Number: 167993
• DSSTox Substance ID: DTXSID00211730
• Nikkaji Number: J519.117C
• Wikidata: Q83086711
• Mol file: 62674-12-8.mol

Synonyms:3,4-Dichloro-2(5H)-furanone;62674-12-8;3,4-dichloro-2H-furan-5-one;3,4-Dichlorofuran-2(5H)-one;3,4-dichloro-2,5-dihydrofuran-2-one;CCRIS 3696;NSC167993;SCHEMBL5467848;2,3-Dichloro-2-buten-4-olide;DTXSID00211730;ULWRZZDLLPNFEW-UHFFFAOYSA-N;AKOS006281417;NSC 167993;NSC-167993;3,4-Dichloro-2(5H)-furanone, 97%;CS-0253606;EN300-6475359;Z1198160971;InChI=1/C4H2Cl2O2/c5-2-1-8-4(7)3(2)6/h1H

Chemical Property of 3,4-Dichloro-2(5H)-furanone

Chemical Property:

• Vapor Pressure: 0.00749mmHg at 25°C
• Melting Point: 48-52°C
• Boiling Point: 268.9°C at 760 mmHg
• Flash Point: 135.4°C
• PSA: 26.30000
• Density: 1.59g/cm³
• LogP: 1.23240
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 151.9431847
• Heavy Atom Count: 8
• Complexity: 161

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,4-Dichlorofuran-2(5H)-one ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 36-43
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1C(=C(C(=O)O1)Cl)Cl

Technology Process of 3,4-Dichloro-2(5H)-furanone

There total 7 articles about 3,4-Dichloro-2(5H)-furanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

Mucochloric acid (766-40-5) → 3,4-dichloro-5H-furan-2-one (62674-12-8)

Guidance literature:

Mucochloric acid; With sodium tetrahydroborate; In methanol; at 0 ℃; for 30h;

With sulfuric acid; In methanol; at 0 ℃; for 0.166667h;

DOI:10.1002/ejoc.200300097

Reference yield: 80.0%

→ 3,4-dichloro-5H-furan-2-one (62674-12-8)

Guidance literature:

Reference yield:

→ 3,4-dichloro-5H-furan-2-one (62674-12-8)

Guidance literature:

With aluminum isopropoxide; isopropyl alcohol;

DOI:10.1021/ja01104a038

upstream raw materials:

Mucochloric acid

mucochloric acid

Downstream raw materials:

4,4'-dichlorobiphenyl

3,4-bis(4-chlorophenyl)-2(5H)-furanone

4,4'-Dimethoxybiphenyl

3,4-di(4-methoxyphenyl)-2,5-dihydrofuran-2-one

Refernces

• 1、 -. "COMPOSITIONS AND METHODS FOR VIRAL SENSITIZATION". Paragraph 0048; sheet 3. . Retrieved 2016/08/23.
• 2、 Bellina, Fabio,Rossi, Renzo. "An efficient and inexpensive multigram synthesis of 3,4-dibromo- and 3,4-dichlorofuran-2(5H)-one". . p. 1887 - 1889. Retrieved 2008/02/12.