3,5-dimethoxy-N-phenylbenzamide

Base Information

• Chemical Name: 3,5-dimethoxy-N-phenylbenzamide
• CAS No.: 87282-04-0
• Molecular Formula: C₁₅H₁₅NO₃
• Molecular Weight: 257.289
• Mol file: 87282-04-0.mol

Synonyms:3,5-dimethoxy-N-phenylbenzamide

Chemical Property of 3,5-dimethoxy-N-phenylbenzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-dimethoxy-N-phenylbenzamide

There total 13 articles about 3,5-dimethoxy-N-phenylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

phenyl carbamate (64-10-8) + 1,3-bis(3,5-dimethoxyphenyl)propane-1,3-dione → 3,5-dimethoxy-N-phenylbenzamide (87282-04-0)

Guidance literature:

With potassium hydroxide; at 135 ℃; for 24h; Schlenk technique;

DOI:10.1039/c4ra14234a

Reference yield: 85.0%

3,5-dimethoxybenzaldehdye (7311-34-4) + nitrobenzene (98-95-3,26969-40-4) → 3,5-dimethoxy-N-phenylbenzamide (87282-04-0)

Guidance literature:

With manganese(IV) oxide; acetic acid; In chloroform; at 60 ℃; for 12h; Inert atmosphere;

DOI:10.1039/c4ob01155d

Reference yield: 78.0%

iodobenzene (591-50-4) + 3,5-dimethoxybenzamide (17213-58-0) → 3,5-dimethoxy-N-phenylbenzamide (87282-04-0)

Guidance literature:

With copper(l) iodide; (E)-3-(dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-one; caesium carbonate; In acetonitrile; at 82 ℃; for 12h; Inert atmosphere;

DOI:10.1055/s-0029-1217958

upstream raw materials:

3,5-dimethoxybenzoyl chloride

aniline

pyridine N-oxide

3,5-Dimethoxy-N-phenyl-benzimidoyl chloride

Downstream raw materials:

3-(3,5-dimethoxyphenyl)acrylic acid

3,5-dimethoxybenzaldehdye

Refernces

• 1、 -. "Interpositus substituted N-aryl benzoyl amines one-step synthesis method of the compound". Paragraph 0017-0020; 0045-0048. . Retrieved 2017/02/28.
• 2、 Yadav, Dilip Kumar T.,Bhanage, Bhalchandra M.. "Base-catalyzed synthesis of amides and imines via C-C and CC bond cleavage". . p. 12387 - 12391. Retrieved 2015/02/19.