5-chloro-2-hydroxybenzaldehyde dimethyl acetal

Base Information

• Chemical Name: 5-chloro-2-hydroxybenzaldehyde dimethyl acetal
• CAS No.: 109165-17-5
• Molecular Formula: C₉H₁₁ClO₃
• Molecular Weight: 202.638
• Mol file: 109165-17-5.mol

Synonyms:5-chloro-2-hydroxybenzaldehyde dimethyl acetal

Chemical Property of 5-chloro-2-hydroxybenzaldehyde dimethyl acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-chloro-2-hydroxybenzaldehyde dimethyl acetal

There total 2 articles about 5-chloro-2-hydroxybenzaldehyde dimethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

methanol (67-56-1) + 4-chloro-2-formylphenyl acetate (60315-73-3) → 5-chloro-2-hydroxybenzaldehyde dimethyl acetal (109165-17-5)

Guidance literature:

With methanol;

Reference yield:

methanol (67-56-1) + 1-<5-chloro-2-hydroxy-α-(3-phenoxybenzoyloxy)benzyl>-1,2,4-triazole → 3-phenoxybenzoic acid (3739-38-6) + 5-chlorosalicyclaldehyde (635-93-8) + 5-chloro-2-hydroxybenzaldehyde dimethyl acetal (109165-17-5)

Guidance literature:

With potassium hydroxide; for 0.333333h; Ambient temperature;

Reference yield:

α-bromoacetophenone (70-11-1) + 5-chloro-2-hydroxybenzaldehyde dimethyl acetal (109165-17-5) → C17H17ClO4

Guidance literature:

With potassium carbonate; In acetone; at 20 ℃;

DOI:10.1039/b801004h

upstream raw materials:

methanol

4-chloro-2-formylphenyl acetate

Downstream raw materials:

C₁₄H₁₁ClO₅

C₁₄H₉ClO₅

Refernces

• 1、 Liepa, Andris J.,Morton, Trevor C.. "Acetal Formation Facilitated in 2-Hydroxyaryl Aldehydes by Intramoleculedar Acyl Group Transfer". . p. 1747 - 1757. Retrieved 2007/10/02.