Guanylthiourea

Base Information Edit

Chemical Name:Guanylthiourea
CAS No.:2114-02-5
Molecular Formula:C2H6N4S
Molecular Weight:118.162
Hs Code.:2930.90
European Community (EC) Number:218-308-0
NSC Number:55743
UNII:LF1NJY8ID8
DSSTox Substance ID:DTXSID50175378
Nikkaji Number:J1.796E
Wikidata:Q27282951
Mol file:2114-02-5.mol

Synonyms:Guanylthiourea;Guthimine;Guthymine;Gutimin;Gutimine

Suppliers and Price of Guanylthiourea

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Imino-4-thiobiuret
5g
$ 50.00

TCI Chemical
Guanylthiourea >98.0%(HPLC)(T)
25g
$ 32.00

TCI Chemical
Guanylthiourea >98.0%(HPLC)(T)
100g
$ 87.00

TCI Chemical
Guanylthiourea >98.0%(HPLC)(T)
500g
$ 228.00

Synthonix
Carbamimidoylthiourea 98%
100g
$ 150.00

Synthonix
Carbamimidoylthiourea 98%
5g
$ 25.00

Synthonix
Carbamimidoylthiourea 98%
25g
$ 50.00

Sigma-Aldrich
2-Imino-4-thiobiuret 99%
25g
$ 39.20

Oakwood
2-Imino-4-thiobiuret 99%
25g
$ 15.00

Matrix Scientific
Carbamimidoylthiourea 98%
25g
$ 30.00

Total 98 raw suppliers

Chemical Property of Guanylthiourea Edit

Chemical Property:

Appearance/Colour:white to off-white crystals or crystalline powder
Vapor Pressure:0.000599mmHg at 25°C
Melting Point:171-173 °C(lit.)
Refractive Index:1.5605 (estimate)
Boiling Point:310.5 °C at 760 mmHg
PKA:11.89±0.70(Predicted)
Flash Point:141.6 °C
PSA：120.01000
Density:1.73 g/cm³
LogP:0.60430
Storage Temp.:Sealed in dry,Room Temperature
Water Solubility.:7 g/100 mL (20 ºC)
XLogP3:-1.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:118.03131738
Heavy Atom Count:7
Complexity:102

Purity/Quality:

99% ^*data from raw suppliers

2-Imino-4-thiobiuret ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi; Xn
Hazard Codes:Xi,Xn
Statements: 36/37/38-20/21/22
Safety Statements: 26-37/39-24/25-23

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C(=NC(=S)N)(N)N
Uses 2-Imino-4-thiobiuret is used in the design and synthesis of guanylthiourea derivatives which are potential inhibitors of plasmodium falciparum dihydrofolate reductase enzyme. 2-Imino-4-thiobiuret is also used as a reagent in recyclization reactions of N-arylmaleimides with polynucleophilic compounds.

Technology Process of Guanylthiourea

There total 17 articles about Guanylthiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 127099-85-8,780722-26-1,461-58-5
N-Cyanoguanidine

: 2114-02-5
amidinothiocarbamide

Guidance literature:: With 1-methyl-pyrrolidin-2-one; hydrogen sulfide; at 70 - 80 ℃;
DOI:10.1002/(SICI)1096-9063(199905)55:5<566::AID-PS949>3.0.CO;2-F

Reference yield: 80.0%

: 37507-70-3
cyanocarboxamidine

: 2114-02-5
amidinothiocarbamide

Guidance literature:: cyanocarboxamidine; With hydrogenchloride; In water; at 20 ℃;

With ammonium hydroxide; Sodium thiosulfate pentahydrate; In water; at 0 ℃; for 1h;