Dynorphin A (1-13)

Base Information

• Chemical Name: Dynorphin A (1-13)
• CAS No.: 72957-38-1
• Molecular Formula: C75H126N24O15
• Molecular Weight: 1603.98
• Hs Code.: 2933998090
• Mol file: 72957-38-1.mol

Synonyms:Dynorphin A(pig), 14-de-L-tryptophan-15-de-L-asparticacid-16-de-L-asparagine-17-de-L-glutamine-;1-13-Dynorphin A (pig);10: PN:WO2005097158 SEQID: 10 unclaimed sequence;121: PN: WO0069900 SEQID: 786unclaimed sequence;122: PN: WO0069900 SEQID: 787 unclaimed sequence;123: PN:US20090048431 SEQID: 122 claimed sequence;12: PN: WO2005094423 SEQID: 29unclaimed sequence;12: PN: WO2005103087 SEQID: 15 unclaimed sequence;12: PN:WO2007025286 SEQID: 11 unclaimed sequence;144: PN: WO0069900 SEQID: 809unclaimed sequence;19: PN: WO0239997 SEQID: 24 unclaimed sequence;22: PN:WO2008008805 SEQID: 22 unclaimed protein;25: PN: WO2007106799 SEQID: 122unclaimed sequence;4131: PN: WO03040165 TABLE: 27a claimed protein;639: PN:US20090175821 SEQID: 786 claimed protein;71: PN: US20090104234 SEQID: 71unclaimed protein;Dyn A(1-13)-OH;Porcine dynorphin A(1-13);Dynorphin A: 1-13, porcine;1-13-Dynorphin A(swine);

Chemical Property of Dynorphin A (1-13)

Chemical Property:

• PKA: 3.31±0.10(Predicted)
• PSA: 661.70000
• Density: 1.39 g/cm³
• LogP: 6.27350
• Storage Temp.: −20°C

Purity/Quality:

99% ^*data from raw suppliers

Dynorphin A Porcine Fragment 1-13 ≥97% (HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of Dynorphin A (1-13)

There total 2 articles about Dynorphin A (1-13) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.3%

Z-Tyr-Gly-Gly-Phe-Leu-Arg(Mds)-Arg(Mds)-Ile-Arg(Mds)-Pro-Lys(Boc)-Leu-Lys(Boc)-OBut (79598-29-1) → dynorphin A-(1-13) (72957-38-1)

Guidance literature:

With methyl-phenyl-thioether; trifluoroacetic acid; at 50 ℃; for 2h;

DOI:10.1248/cpb.29.2592

Reference yield:

→ dynorphin A-(1-13) (72957-38-1)

Guidance literature:

upstream raw materials:

Z-Tyr-Gly-Gly-Phe-Leu-Arg(Mds)-Arg(Mds)-Ile-Arg(Mds)-Pro-Lys(Boc)-Leu-Lys(Boc)-OBut

Refernces

• 1、 Wakimasu,Kitada,Fujino. "Use of the 4-methoxy-2,6-dimethylbenzenesulfonyl (Mds) group to synthesize dynorphin [1-13] and related peptides". . p. 2592 - 2597. Retrieved 2007/10/02.