Benzenesulfonyl azide,4-chloro-

Base Information

• Chemical Name: Benzenesulfonyl azide,4-chloro-
• CAS No.: 4547-68-6
• Molecular Formula: C₆H₄ClN₃O₂S
• Molecular Weight: 217.636
• Mol file: 4547-68-6.mol

Synonyms:

Chemical Property of Benzenesulfonyl azide,4-chloro-

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenesulfonyl azide,4-chloro-

There total 8 articles about Benzenesulfonyl azide,4-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-chloro-benzenesulfonic acid (98-66-8) → p-chlorobenzenesulfonyl azide (4547-68-6)

Guidance literature:

4-chloro-benzenesulfonic acid; With trichloroisocyanuric acid; triphenylphosphine; In tetrahydrofuran; at 0 - 5 ℃;

With sodium azide; In tetrahydrofuran; at 5 - 20 ℃;

DOI:10.1080/17415993.2013.801476

Reference yield: 92.0%

4-chlorobenzenesulfonyl chloride (98-60-2) → p-chlorobenzenesulfonyl azide (4547-68-6)

Guidance literature:

With sodium azide; In water; acetone; at 0 - 20 ℃; for 16h;

DOI:10.1021/ja4042109

Reference yield: 74.0%

4-Chlorobenzenesulfonamide (98-64-6) → p-chlorobenzenesulfonyl azide (4547-68-6)

Guidance literature:

With 3-azidosulfonyl-3H-imidazole-1-ium hydrogen sulfate; potassium carbonate; In water; isopropyl alcohol; at 20 ℃; for 18h;

DOI:10.1021/jo500553q

upstream raw materials:

p-chlorophenylsulfonyl hydrazide

4-chlorobenzenesulfonyl chloride

4-chloro-benzenesulfonic acid

p-Chlorothiophenol

Downstream raw materials:

N-(1-naphthyl)-4-chlorobenzenesulfonamide

N-(2,5-dimethylphenyl)-4-chlorobenzene sulfonamide

4-chloro-N-phenyl-benzenesulfonamide

N?(2?aminophenyl)?4?chlorobenzenesulfonamide

Refernces

• 1、 Jiang, Shuai,Cao, Wen-Bin,Li, Hai-Yan,Xu, Xiao-Ping,Ji, Shun-Jun. "Convenient synthesis of spiroindolenines from tryptamine-derived isocyanides and organic azides by cobalt catalysis in pure water". supporting information. p. 2619 - 2623. Retrieved 2021/04/21.
• 2、 Sreerama, Rakesh,Narasimha Swamy,Ravinder,Vasudeva Reddy,Narsimha, Sirassu. "One-pot synthesis of sulfonyl-1H-1,2,3-triazolyl-thiomorpholine 1,1-dioxide derivatives and evaluation of their biological activity". . p. 455 - 460. Retrieved 2020/12/17.