Valpromide

Base Information Edit

Chemical Name:Valpromide
CAS No.:2430-27-5
Molecular Formula:C8H17NO
Molecular Weight:143.229
Hs Code.:2924199090
European Community (EC) Number:219-394-2
UNII:RUA6CWU76G
DSSTox Substance ID:DTXSID1023734
Nikkaji Number:J7.891C
Wikipedia:Valpromide
Wikidata:Q847560
NCI Thesaurus Code:C152822
Metabolomics Workbench ID:148636
ChEMBL ID:CHEMBL93836
Mol file:2430-27-5.mol

Synonyms:Depamide;dipropylacetamide;valproic acid amide;valpromide

Suppliers and Price of Valpromide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Valpromide
10mg
$ 75.00

Sigma-Aldrich
Valpromide ≥97% (NMR)
10mg
$ 72.10

Sigma-Aldrich
Valpromide ≥97% (NMR)
50mg
$ 290.00

Medical Isotopes, Inc.
Valpromide
25 mg
$ 1500.00

Medical Isotopes, Inc.
Valpromide
5 mg
$ 950.00

ChemScene
Valpromide ≥98.0%
10mg
$ 50.00

ChemScene
Valpromide ≥98.0%
50mg
$ 70.00

ChemScene
Valpromide ≥98.0%
100mg
$ 90.00

Biosynth Carbosynth
2,2-Di-N-propylacetamide
100 g
$ 500.00

Biosynth Carbosynth
2,2-Di-N-propylacetamide
250 g
$ 1000.00

Total 49 raw suppliers

Chemical Property of Valpromide Edit

Chemical Property:

Vapor Pressure:0.00535mmHg at 25°C
Melting Point:123-125 °C
Refractive Index:1.44
Boiling Point:274.612 °C at 760 mmHg
PKA:16.76±0.50(Predicted)
Flash Point:119.881 °C
PSA：43.09000
Density:0.885 g/cm³
LogP:2.38840
Storage Temp.:room temp
Solubility.:DMSO: >10mg/mL
Water Solubility.:Soluble in chloroform, dimethyl sulfoxide and methanol. Insoluble in water.
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:5
Exact Mass:143.131014166
Heavy Atom Count:10
Complexity:95.4

Purity/Quality:

99% ^*data from raw suppliers

Valpromide ^*data from reagent suppliers

Safty Information:

Pictogram(s): R22:Harmful if swallowed.;
Hazard Codes:Xn
Statements: 22
Safety Statements: 22-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCCC(CCC)C(=O)N
Uses Antiepileptic; anticonvulsant. Valpromide is a reactant used in the synthesis of mutual prodrugs containing bio-cleavable and drug releasable disulfide linkers.

Technology Process of Valpromide

There total 8 articles about Valpromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 99-66-1
valproic acid

: 40755-20-2
2-propylpentan-1-amine

: 2430-27-5
valpromide

: bis(2-propylpentyl)amine

Guidance literature:: valproic acid; With cyclopentyl methyl ether; ammonia; at 200 ℃; under 4500.45 Torr; Sealed tube; Green chemistry;

With cyclopentyl methyl ether; ammonia; hydrogen; at 200 ℃; for 120h; under 42004.2 Torr; Cooling with ice; Green chemistry;
DOI:10.1039/d0gc01441a

Reference yield: 82.0%

: 99-66-1
valproic acid

: 40755-20-2
2-propylpentan-1-amine

: 2430-27-5
valpromide

Guidance literature:: valproic acid; With cyclopentyl methyl ether; ammonia; at 200 ℃; under 4500.45 Torr; Sealed tube; Green chemistry;

With cyclopentyl methyl ether; ammonia; hydrogen; at 200 ℃; for 6.5h; under 42004.2 Torr; Cooling with ice; Green chemistry;
DOI:10.1039/d0gc01441a