Tris(4-methoxyphenyl)phosphine

Base Information

• Chemical Name: Tris(4-methoxyphenyl)phosphine
• CAS No.: 855-38-9
• Deprecated CAS: 24342-83-4
• Molecular Formula: C21H21O3P
• Molecular Weight: 352.37
• Hs Code.: HOSPHINE PRODUCT IDENTIFICATION
• European Community (EC) Number: 212-723-0
• NSC Number: 136458
• UNII: PF5BT47LZ8
• DSSTox Substance ID: DTXSID3061217
• Nikkaji Number: J151.204H
• Wikipedia: Tris(4-methoxyphenyl)phosphine
• Wikidata: Q72515244
• Mol file: 855-38-9.mol

Synonyms:Tris(4-methoxyphenyl)phosphine;855-38-9;Phosphine, tris(4-methoxyphenyl)-;Trianisylphosphine;tris(4-methoxyphenyl)phosphane;Tri-p-anisylphosphine;Tris(p-anisyl)phosphine;tris(p-Methoxyphenyl)phosphine;Phosphine, tris(p-methoxyphenyl)-;TRI(4-METHOXYPHENYL)PHOSPHINE;EINECS 212-723-0;MFCD00014896;NSC 136458;PF5BT47LZ8;Tri(p-methoxyphenyl)phosphine;NSC-136458;AI3-62578;P(p-anisyl)3;NSC136458;Tris(4-anisyl)phosphine;UNII-PF5BT47LZ8;SCHEMBL50047;tri-(4-Methoxyphenyl)phosphine;tris(p-methoxyphenyl) phosphine;tris (4-methoxyphenyl)phosphine;tris(4-methoxyphenyl) phosphine;DTXSID3061217;Phosphorus tri-(p-methoxyphenyl);AMY23386;BCP22502;Tris(4-methoxyphenyl)phosphine, 95%;AKOS015851826;CS-W014488;GC10067;AS-10205;SY023707;FT-0633033;FT-0653342;T0861;F10276;EN300-7411599;J-525132;TRI(P-ANISYL)PHOSPHINE;TRIS(4-METHOXYPHENYL)PHOSPHANE;TRIS(4-METHOXYPHENYL)PHOSPHINE;TRIS(P-ANISYL)PHOSPHINE;TRIS(P-METHOXYPHENYL)PHOSPHINE

Chemical Property of Tris(4-methoxyphenyl)phosphine

Chemical Property:

• Appearance/Colour: White to pale yellow crystalline powder
• Vapor Pressure: 3.93E-08mmHg at 25°C
• Melting Point: 131-134°C(lit.)
• Boiling Point: 457.8 °C at 760 mmHg
• Flash Point: 287.3 °C
• PSA: 41.28000
• Density: 131-134 °C(lit.)
• LogP: 3.47060
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Air Sensitive
• Water Solubility.: Insoluble in water.
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 352.12283153
• Heavy Atom Count: 25
• Complexity: 310

Purity/Quality:

99% ^*data from raw suppliers

Tris(4-methoxyphenyl)phosphine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)P(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC
• Uses: suzuki reaction Tris(4-methoxyphenyl)phosphine is a useful intermediate employed in organic synthesis and in other chemical processes.

Technology Process of Tris(4-methoxyphenyl)phosphine

There total 14 articles about Tris(4-methoxyphenyl)phosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

→ P(p-CH3OC6H4)3 (855-38-9)

Guidance literature:

Reference yield: 94.0%

Tris(4-methoxyphenyl)phosphine oxide (803-17-8) → P(p-CH3OC6H4)3 (855-38-9)

Guidance literature:

Tris(4-methoxyphenyl)phosphine oxide; With trityl tetrakis(pentafluorophenyl)borate; In ⁽²⁾H₈-toluene; at 20 ℃; Glovebox; Inert atmosphere;

With phenylsilane; In ⁽²⁾H₈-toluene; at 80 ℃; for 5h; Glovebox; Inert atmosphere; Sealed tube;

DOI:10.1002/adsc.202100189

Reference yield: 89.0%

1-bromo-4-methoxy-benzene (104-92-7) → P(p-CH3OC6H4)3 (855-38-9)

Guidance literature:

With phosphorus trichloride;

DOI:10.1021/jo00116a042

upstream raw materials:

4-methoxyphenyl magnesium bromide

1-bromo-4-methoxy-benzene

p-methoxyphenyllithium

(4-methoxyphenyl)zinc(II) bromide

Downstream raw materials:

Isocyanatomethyl-tris-(4-methoxy-phenyl)-phosphonium; chloride

ethyl (E)-3-(4-methoxyphenyl)prop-2-enoate

tris-p-methoxyphenylphosphine sulphide

diphenyldisulfane

Refernces

• 1、 Landais, Yannick,Laye, Claire,Lusseau, Jonathan,Robert, Frédéric. "The Trityl-Cation Mediated Phosphine Oxides Reduction". supporting information. p. 3035 - 3043. Retrieved 2021/05/10.
• 2、 Mayer, Robert J.,Hampel, Nathalie,Ofial, Armin R.. "Lewis Acidic Boranes, Lewis Bases, and Equilibrium Constants: A Reliable Scaffold for a Quantitative Lewis Acidity/Basicity Scale". supporting information. p. 4070 - 4080. Retrieved 2021/01/29.