Disulfamide

Base Information

• Chemical Name: Disulfamide
• CAS No.: 671-88-5
• Molecular Formula: C7H9ClN2O4S2
• Molecular Weight: 284.744
• European Community (EC) Number: 211-585-9
• NSC Number: 38904
• UNII: 26POQ4GICP
• DSSTox Substance ID: DTXSID90217408
• Nikkaji Number: J7.086F
• Wikidata: Q27254118
• NCI Thesaurus Code: C65440
• ChEMBL ID: CHEMBL2104258
• Mol file: 671-88-5.mol

Synonyms:Disulfamide;Disulphamide;671-88-5;Disamide;Desamide;Diuroblitz;Fisiuretik;Tolclotidum;Toluidrin;Edemil;Toluren;Natirene 25;Diurex (Eisai);Disulfamide (VAN);Disulfamide [INN];5-Chlorotoluene-2,4-disulfonamide;Disulfamida;Disulfamidum;5-Chloro-2,4-disulfamoyltoluene;Disulfamidum [INN-Latin];4-chloro-6-methylbenzene-1,3-disulfonamide;C7H9ClN2O4S2;Disulfamida [INN-Spanish];Disulfamide (pharmaceutical);1,3-Benzenedisulfonamide, 4-chloro-6-methyl-;Toluene-2,4-disulfamoyltoluene;5-Chloro-2,4-disulfamyltoluene;4-Chloro-6-methyl-1,3-benzenedisulfonamide;Disulfamide [INN:BAN];EINECS 211-585-9;UNII-26POQ4GICP;NSC 38904;NSC-38904;26POQ4GICP;Toluene-2,4-disulfonamide, 5-chloro-;BRN 2702245;4-11-00-00559 (Beilstein Handbook Reference);Disulfamid;Disulfamide (BAN);TOLCLOTIDE;DISULFAMIDE [MI];Toluene-2, 5-chloro-;1, 4-chloro-6-methyl-;SCHEMBL309326;CHEMBL2104258;DTXSID90217408;CHEBI:135178;C7-H9-Cl-N2-O4-S2;NSC38904;ZINC01482043;HY-137364;LS-154065;CS-0138117;FT-0725338;D02478;Q27254118

Chemical Property of Disulfamide

Chemical Property:

• Vapor Pressure: 4.04E-12mmHg at 25°C
• Melting Point: 260°
• Boiling Point: 549.4°C at 760 mmHg
• PKA: 9.34±0.60(Predicted)
• Flash Point: 286.1°C
• PSA: 137.08000
• Density: 1.621g/cm³
• LogP: 3.50540
• XLogP3: 0
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 283.9692268
• Heavy Atom Count: 16
• Complexity: 450

Purity/Quality:

99% ^*data from raw suppliers

4-CHLORO-6-METHYL-1,3-BENZENEDISULFONAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1S(=O)(=O)N)S(=O)(=O)N)Cl
• Uses: Disulfamide is a prodrug useful in the treatment of diseases.

Technology Process of Disulfamide

There total 3 articles about Disulfamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-chloro-toluene-2,4-disulfonyl chloride (13940-86-8) → Disamid (671-88-5)

Guidance literature:

With ammonia;

Reference yield:

1-chloro-3-methylbenzene (108-41-8) → Disamid (671-88-5)

Guidance literature:

Multi-step reaction with 2 steps

1: NaCl; ClSO₃H

2: NH₃

With chlorosulfonic acid; ammonia; sodium chloride;

Reference yield:

→ Disamid (671-88-5)

Guidance literature:

entspr. Dichlorid, konz. NH3, 20grad;

upstream raw materials:

5-chloro-toluene-2,4-disulfonyl chloride

1-chloro-3-methylbenzene

Downstream raw materials:

1,3-Bis-(N-butyl-N'-sulfonylureido)-6-chlor-4-methyl-benzol

Refernces