Technology Process of ethyl 7,8,9-trimethoxy-3-phenyl-5,6-dihydropyrrolo[2, 1-a]isoquinoline-2-carboxylate
There total 6 articles about ethyl 7,8,9-trimethoxy-3-phenyl-5,6-dihydropyrrolo[2, 1-a]isoquinoline-2-carboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium diacetate; caesium carbonate; triphenylphosphine;
In
1,4-dioxane;
at 80 ℃;
for 21.25h;
Inert atmosphere;
Sealed tube;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: ammonium acetate / 2 h / 50 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 65 °C / Inert atmosphere; Reflux
3: sodium hydrogencarbonate / 36 h / 20 °C
4: trichlorophosphate / toluene / 3 h / 90 - 120 °C / Inert atmosphere
5: potassium carbonate / acetonitrile / 2 h / Reflux
6: palladium diacetate; caesium carbonate; triphenylphosphine / 1,4-dioxane / 21.25 h / 80 °C / Inert atmosphere; Sealed tube
With
lithium aluminium tetrahydride; ammonium acetate; palladium diacetate; sodium hydrogencarbonate; potassium carbonate; caesium carbonate; triphenylphosphine; trichlorophosphate;
In
tetrahydrofuran; 1,4-dioxane; toluene; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium carbonate / acetonitrile / 2 h / Reflux
2: palladium diacetate; caesium carbonate; triphenylphosphine / 1,4-dioxane / 21.25 h / 80 °C / Inert atmosphere; Sealed tube
With
palladium diacetate; potassium carbonate; caesium carbonate; triphenylphosphine;
In
1,4-dioxane; acetonitrile;